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Insect antifeedant activity of clerodane diterpenes and related model compounds
December 2002
December 2002
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Abstract
A comprehensive compilation of all test results on the insect antifeedant activity
of clerodane diterpenes and related model compounds is reported. To increase the compatibility
of data from different sources, some of the results reported in the literature have
been converted into a standardized form. The compounds were sorted into groups according
to the different types of sidechain attached to C-9. Despite the wealth of information,
collected in 15 tables, it remains difficult to assign importance to separate structural
elements in relation to the observed antifeedant activity. A detailed analysis of
the structure-activity relationships could not be presented, but some interesting
trends can be distinguished based on the structures of the strongest antifeedants.
The compilation covers the literature up to December 2001.