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Abstract
The American Congress of Obstetricians and Gynecologists recommends that all pregnant
women be offered aneuploidy screening or diagnostic testing. A myriad of screening
and testing options are available to patients based on their risk profile and gestational
age. Screening options include traditional serum analyte screening, such as first-trimester
screening or quadruple screening, and more recently, cell-free DNA. Diagnostic testing
choices include chorionic villus sampling and amniocentesis. The number of screening
and diagnostic modalities complicates prenatal counseling for physicians and can be
difficult for patients to grasp. Appropriate pretest and posttest counseling is important
to ensure adequate understanding of results and ensure testing strategy is concordant
with patient goals.
Journal ID (iso-abbrev): Obstet. Gynecol. Clin. North Am.
Title:
Obstetrics and gynecology clinics of North America
ISSN
(Print):
0889-8545
ISSN
(Electronic):
1558-0474
Publication date Nihms-submitted: 2
July
2017
Publication date
(Print):
June
2017
Publication date PMC-release: 08
August
2017
Volume: 44
Issue: 2
Pages: 245-256
Affiliations
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University
of North Carolina School of Medicine, 3010 Old Clinic Building, CB #7516, Chapel Hill,
NC 27599-7516, USA