Isolation and Characterization of Viruses Related to the SARS Coronavirus from Animals in Southern China

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Abstract

A novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome (SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal market in Guangdong, China. Evidence of virus infection was also detected in other animals (including a raccoon dog, Nyctereutes procyonoides) and in humans working at the same market. All the animal isolates retain a 29-nucleotide sequence that is not found in most human isolates. The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known.

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Journal

Title: Science

Abbreviated Title: Science

Publisher: American Association for the Advancement of Science (AAAS)

ISSN (Print): 0036-8075

ISSN (Electronic): 1095-9203

Publication date Created: October 10 2003

Publication date (Print): October 10 2003

Volume: 302

Issue: 5643

Pages: 276-278

Article

DOI: 10.1126/science.1087139

PubMed ID: 12958366

SO-VID: 2613b34d-9e38-474b-8320-6e7e418d1a7e

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