MRSA strains with distinct accessory genes predominate at different ages in cystic fibrosis.

Porterfield, Harry S.; Maakestad, Lucas J; LaMarche, Mason M; Thurman, Andrew L.; Kienenberger, Zoe E; Pitcher, Nicholas J; Hansen, Alexis R.; Zirbes, Christian F; Boyken, Linda; Muyskens, Bethany L; Pezzulo, Alejandro A; Singh, Sachinkumar B.; Twait, Erik; Ford, Bradley; Diekema, Daniel J; Reeb, Valérie; Fischer, Anthony J

doi:10.1002/ppul.25559

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MRSA strains with distinct accessory genes predominate at different ages in cystic fibrosis.

Author(s): Harry S Porterfield ¹ ^, ² , Lucas J Maakestad ³ , Mason M LaMarche ³ , Andrew L Thurman ⁴ , Zoe E Kienenberger ³ , Nicholas J Pitcher ³ , Alexis R Hansen ³ , Christian F Zirbes ³ , Linda Boyken ¹ , Bethany L Muyskens ³ , Alejandro A Pezzulo ⁴ , Sachinkumar B Singh ³ , Erik Twait ⁵ , Bradley Ford ¹ , Daniel J Diekema ⁴ , Valérie Reeb ⁵ , Anthony J Fischer ³

Publication date (Electronic): Sep 2021

Journal: Pediatric pulmonology

Publisher: Wiley

Keywords: MRSA, Staphylococcus aureus, birth cohort effect, cystic fibrosis, whole genome sequencing

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Abstract

Methicillin resistant Staphylococcus aureus (MRSA) is prevalent and consequential in cystic fibrosis (CF). Whole genome sequencing (WGS) could reveal genomic differences in MRSA associated with poorer outcomes or detect MRSA transmission.

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Journal ID (iso-abbrev): Pediatr Pulmonol

Title: Pediatric pulmonology

Publisher: Wiley

ISSN (Electronic): 1099-0496

ISSN (Print): 1099-0496

Publication date (Electronic): Sep 2021

Volume: 56

Issue: 9

Affiliations

[1 ] Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.

[2 ] Department of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, Maryland, USA.

[3 ] Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.

[4 ] Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.

[5 ] State Hygienic Laboratory at the University of Iowa, Iowa City, Iowa, USA.

Article

Mid ID: NIHMS1721372

DOI: 10.1002/ppul.25559

PMC ID: 8395597

PubMed ID: 34219414

SO-VID: 2580f0f2-c315-4e2c-ac69-4cffac4bd199

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Keywords: cystic fibrosis,MRSA,whole genome sequencing,birth cohort effect,Staphylococcus aureus

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Keywords: cystic fibrosis, MRSA, whole genome sequencing, birth cohort effect, Staphylococcus aureus

MRSA strains with distinct accessory genes predominate at different ages in cystic fibrosis.

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