Current state of knowledge on Takotsubo syndrome: a Position Statement from the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the European Society of Cardiology.

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Abstract

Takotsubo syndrome is an acute reversible heart failure syndrome that is increasingly recognized in modern cardiology practice. This Position Statement from the European Society of Cardiology Heart Failure Association provides a comprehensive review of the various clinical and pathophysiological facets of Takotsubo syndrome, including nomenclature, definition, and diagnosis, primary and secondary clinical subtypes, anatomical variants, triggers, epidemiology, pathophysiology, clinical presentation, complications, prognosis, clinical investigations, and treatment approaches. Novel structured approaches to diagnosis, risk stratification, and management are presented, with new algorithms to aid decision-making by practising clinicians. These also cover more complex areas (e.g. uncertain diagnosis and delayed presentation) and the management of complex cases with ongoing symptoms after recovery, recurrent episodes, or spontaneous presentation. The unmet needs and future directions for research in this syndrome are also discussed.

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Author and article information

Journal

Journal ID (iso-abbrev): Eur. J. Heart Fail.

Title: European journal of heart failure

ISSN (Electronic): 1879-0844

ISSN (Print): 1388-9842

Publication date (Electronic): Jan 2016

Volume: 18

Issue: 1

Affiliations

[1 ] National Heart and Lung Institute, Imperial College, London, UK.

[2 ] NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, UK.

[3 ] Cardiology Division, 'Cava de Tirreni and Amalfi Coast' Hospital, Heart Department, University of Salerno, Italy.

[4 ] Medizinische Klinik II, Sana Kliniken Lübeck, Germany.

[5 ] Department of Cardiology, Robert Bosch Krankenhaus, Stuttgart, Germany.

[6 ] University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', Heart Department, Largo Città di Ippocrate, Salerno, Italy.

[7 ] Department of Cardiovascular Pathology, St George's University Medical School, London, UK.

[8 ] North Shore Heart Research, Kolling Institute, University of Sydney, Australia.

[9 ] Department of Cardiology, Royal North Shore Hospital, Sydney, Australia.

[10 ] Invasive Cardiology, Careggi Hospital, Florence, Italy.

[11 ] Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.

[12 ] Clinic for Cardiology, University Hospital Zurich, Zurich, Switzerland.

[13 ] Department of Cardiology, Attikon University Hospital, University of Athens Medical School, Athens, Greece.

[14 ] Université Paris Diderot; U942 Inserm, Département d'Anestéhsie-Réanimation Hôpitaux Universitaires Saint Louis-Lariboisière, Paris, France.

[15 ] Department of Molecular and Clinical Medicine/Cardiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Article

DOI: 10.1002/ejhf.424

PubMed ID: 26548803

SO-VID: 25085873-20fe-4266-8bf6-0e16d9a1e406

History

Keywords: Takotsubo syndrome,heart failure,risk stratification,stress

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Keywords: Takotsubo syndrome, heart failure, risk stratification, stress

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