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      High frequency volume coils for clinical NMR imaging and spectroscopy

      , , , ,
      Magnetic Resonance in Medicine
      Wiley

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          Abstract

          A tuned transmission line resonator has been developed in theory and in practical design for the clinical NMR volume coil application at 4.1 tesla. The distributed circuit transmission line resonator was designed for high frequency, large conductive volume applications where conventional lumped element coil designs perform less efficiently. The resonator design has made use of a resonant coaxial cavity, which could be variably tuned to the Larmor frequency of interest by tunable transmission line elements. Large head- and body-sized volumes, high efficiencies, and broad tuning ranges have been shown to be characteristic of the transmission line resonator to frequencies of 500 MHz. The B1 homogeneity of the resonator has been demonstrated to be a function of the electromagnetic properties of the load itself. By numerically solving Maxwell's equations for the fully time-dependent B1 field, coil homogeneity was predicted with finite-element models of anatomic structure, and inhomogeneities corrected for. A how-to exposition of coil design and construction has been included. Simple methods of quadrature driving and double tuning the transmission line resonator have also been presented. Human head images obtained with a tuned transmission line resonator at 175 MHz have clearly demonstrated uncompromised high field advantages of signal-to-noise and spatial resolution.

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          In vivo magnetic resonance imaging and spectroscopy of humans with a 4 T whole-body magnet.

          A research-type 4 T whole-body magnet, built by Siemens AG, Erlangen, FRG, was used to investigate magnetic resonance at high field strengths. Designs for head and body coils operating at 170 MHz are described. Proton images of the human head and body are degraded by dielectric resonances and penetration effects. The nature of the dielectric resonances was demonstrated in phantoms containing distilled and saline doped water. Radiation damping at 170 MHz generates secondary echoes after a spin echo sequence. This effect was observed in phantoms and with reduced amplitude in the human head. Hydrogen spectra of the human head were selected utilizing stimulated and spin echoes. The latter technique allows the volume size to be reduced to 1 cm3. Examples of brain tumors that have been routinely investigated with volumes of 8 cm3 are given. Natural abundance carbon and phosphorus spectra of muscle and liver demonstrate the expected increase in spectral resolution and signal to noise ratio. Carbon spectra from the liver show the glycogen signal. Fluorine spectroscopy was used to study the time course of the absorption and emptying of a fluorinated antibiotic from the human stomach.
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            Slotted tube resonator: A new NMR probe head at high observing frequencies

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              Spectroscopy and imaging with a 4 tesla whole-body MR system.

              Magnetic resonance (MR) spectroscopy and imaging experiments on humans were performed with a whole-body MR system at a static field of 4 tesla. Spectroscopic studies focussed on 1H, 13C, and 31P. Imaging of humans turned out to be possible, although below the optimum at this field. This holds especially for body imaging, since RF penetration effects and dielectric resonances influence the RF field homogeneity. Excellent volume selective proton spectra of the human cerebrum and cerebellum were obtained using the stimulated echo method. Natural abundance carbon spectra of the human calf were acquired both undecoupled and with narrowband decoupling, resolving the various triglyceride resonances. Broadband decoupling, however, would have violated SAR guidelines. Liver glycogen was detected on natural abundance 13C spectra.
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                Author and article information

                Journal
                Magnetic Resonance in Medicine
                Magn. Reson. Med.
                Wiley
                07403194
                15222594
                August 1994
                August 1994
                : 32
                : 2
                : 206-218
                Article
                10.1002/mrm.1910320209
                7968443
                24b9bc91-b418-4275-aa46-2e26b465165e
                © 1994

                http://doi.wiley.com/10.1002/tdm_license_1.1

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