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A phase I clinical trial of the treatment of Crohn's fistula by adipose mesenchymal stem cell transplantation.
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Abstract
The effective management of fistulas in patients with Crohn's disease presents an extremely challenging problem. Mesenchymal adult stem cells extracted from certain tissues, such as adipose tissue, can differentiate into various cell types. Therefore, we have tried to use such cells to stimulate healing of Crohn's fistulas.