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      Unsatisfactory colposcopy and the response to orally administered oestrogen: a randomized double blind placebo controlled trial.

      1 , , ,
      British journal of obstetrics and gynaecology
      Wiley

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          Abstract

          Thirty-six women with dyskaryotic cervical smears and unsatisfactory colposcopy were randomly allocated to receive either 30 micrograms ethinyl oestradiol or placebo daily by mouth for 10 days. Thirty-four women were available for review (17 women in each of the two groups), full colposcopic inspection of the transformation zone was possible in a significantly greater proportion of the oestrogen treated group (70% versus 23%, P less than 0.01). As most diagnostic conizations are currently performed on the basis of unsatisfactory colposcopy, the use of oestrogen medication followed by colposcopic reassessment should permit a reduction in the number of patients subject to operation.

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          Author and article information

          Journal
          Br J Obstet Gynaecol
          British journal of obstetrics and gynaecology
          Wiley
          0306-5456
          0306-5456
          Aug 1990
          : 97
          : 8
          Affiliations
          [1 ] Department of Obstetrics and Gynaecology, Northern General Hospital, Sheffield.
          Article
          10.1111/j.1471-0528.1990.tb16248.x
          2205290
          231d0a36-379e-4fb4-8c63-265f9a08afd4
          History

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