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CCR5 Δ32 homozygous cord blood allogeneic transplantation in a patient with HIV: a case report
Rafael F Duarte ,
María Salgado ,
Isabel Sánchez-Ortega ,
Montserrat Arnan ,
Carmen Canals ,
Eva Domingo-Domenech ,
Alberto Fernández-de-Sevilla ,
Eva González-Barca ,
Sara Morón-López ,
Nuria Nogues ,
Beatriz Patiño ,
Maria Carmen Puertas ,
Bonaventura Clotet ,
Lawrence D Petz ,
Sergio Querol ,
Javier Martinez-Picado
June 2015
June 2015
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Abstract
Allogeneic donor CCR5 Δ32 homozygous haemopoietic cell transplantation (HCT) provides
the only evidence to date of long-term control of HIV infection. However, availability
of conventional CCR5 Δ32 homozygous donors is insufficient to develop this as a therapeutic
strategy further.