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      Successful treatment of focal renal artery fibromuscular dysplasia by balloon dilatation demonstrated via fractional flow reserve

      case-report

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          Abstract

          We present a rare case of fibromuscular dysplasia (FMD) manifesting in the mid segment of right renal artery, which led to the development of refractory hypertension. The patient received balloon angioplasty to a severe lesion on the middle of right renal artery and subsequently had normalisation of blood pressures. Fractional flow reserve (FFR) detection of the renal artery before and after balloon dilatation was 0.71 and 0.98, respectively. The patient showed renal artery stenosis (RAS) with distal tumour-like dilatation, and multiple tortuosity and stenosis in carotid artery and coronary artery. At follow-up 2 months later, her blood pressures had normalised.

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          Most cited references11

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          Fibromuscular dysplasia: state of the science and critical unanswered questions: a scientific statement from the American Heart Association.

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            European consensus on the diagnosis and management of fibromuscular dysplasia.

            The main objectives of this expert consensus are to raise awareness about fibromuscular dysplasia, which is more frequent and more often systemic than previously thought and can sometimes have devastating consequences; to provide up-to-date recommendations for the diagnosis, evaluation, and management of the disease; and to identify research priorities. The emphasis has been put on recommendations for daily practice. The main topics covered include definition, classification, diagnosis, and management of fibromuscular dysplasia in adult patients with symptomatic involvement of the renal arteries, supra-aortic trunks, and digestive and peripheral arteries.
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              Assessment of renal artery stenosis severity by pressure gradient measurements.

              The purpose of this study was to define "significant" renal artery stenosis (i.e., a stenosis able to induce arterial hypertension).
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                Author and article information

                Contributors
                Role: deputy chief physician
                Role: attending physician
                Role: medical professor
                Role: medical professor
                Journal
                Clin Med (Lond)
                Clin Med (Lond)
                Clinical Medicine
                Royal College of Physicians
                1470-2118
                1473-4893
                15 March 2024
                November 2023
                15 March 2024
                : 23
                : 6
                : 625-629
                Affiliations
                [A ]Beijing Friendship Hospital, Capital Medical University, Beijing, China
                Author notes
                [* ]Address for correspondence: Rongchong Huang, Department of Cardiology, Cardiovascular Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China. rchuang@ 123456ccmu.edu.cn
                Article
                S1470-2118(24)00038-1
                10.7861/clinmed.2023-0403
                11046610
                38065595
                210e25e9-45ce-430d-9dfc-49ca2e39bdc4
                © 2023 © 2023 THE AUTHORS. Published by Elsevier Limited on behalf of the Royal College of Physicians.

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                Categories
                Lesson of the Month

                fibromuscular dysplasia,renal artery stenosis,ffr-guided renal artery balloon dilatation

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