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      Endoscopic Submucosal Dissection of the Angiolipoma at Hypopharynx-Esophageal Introitus

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          Abstract

          Angiolipoma in the region of the hypopharynx-esophageal introitus is a rare occurrence. Surgical treatment was performed in the few cases reported in the literature. Endoscopic submucosal dissection (ESD) is a minimally invasive treatment for hypopharyngeal and esophageal lesions. Our objective was to evaluate the feasibility, safety, and efficacy of ESD for treatment of angiolipoma at the hypopharynx-esophageal introitus. The patients with submucosal tumors at the hypopharynx-esophageal introitus were diagnosed as angiolipoma by preoperative evaluation with endoscopy, endoscopic ultrasonography, and computed tomography (CT). The patients who were diagnosed with angiolipoma agreed to undergo endoscopic submucosal dissection. Under general anesthesia and endotracheal intubation, ESD was used to remove the lesions. Preoperative, intraoperative, and postoperative data were collected and analyzed to evaluate the feasibility, safety, and effectiveness of endoscopic submucosal dissection. From January 2013 to December 2018, 6 cases of angiolipoma were treated with ESD with a success rate of 100%. The average operation time was 107.0 ± 69.4 minutes. Intraoperative blood loss is the main risk. Endoscopic thermocoagulation successfully stopped bleeding in all cases. Pharyngeal pain and painful swallowing were the main clinical signs. There was no stricture at the hypopharynx-esophageal introitus after the operation. ESD treatment of angiolipoma at hypopharynx-esophageal introitus is feasible, safe, and effective.

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          Two entities in angiolipoma. A study of 459 cases of lipoma with review of literature on infiltrating angiolipoma.

          Chin Lin, F Lin (1974)
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            Oral lipomas in a Brazilian population: a 10-year study and analysis of 450 cases reported in the literature.

            Lipomas are common benign mesenchymal neoplasms that rarely occur in the oral cavity and correspond to less than 4.4% of all benign oral soft tissue tumors. This study describes the clinical, radiological and histological features of cases of oral lipomas seen over a period of 10 years and compared the findings with those reported in the literature. All cases of oral lipomas seen between 1999 and 2009 were retrieved from the archives of the Stomatology Division of the Federal University of Ceará, Brazil. Age, gender, tumor location, clinical findings, duration, histological subtypes, and treatment outcome were recorded. In addition, the English-language literature was searched for studies published between 1966 and 2009. Ten patients (6 women and 4 men) were enrolled in this study. The mean age was 53.4 years (range: 21- 73 years). The specific sites involved were the oral mucosa (n=5), vestibule (n=3), gingiva (n=1), and retromolar region (n=1). The mean size of the tumors was 1.94 cm (range 1.0 to 3.0 cm). Radiographically, only one case appeared as a radiolucent area on occlusal film. Microscopically, 4 cases were classified as simple lipoma, 4 as fibrolipoma, 1 as myxoid lipoma, and 1 as angiolipoma. The duration of the tumors ranged from 2 to 84 months, with a mean duration of 30.4 months. All cases were treated by simple surgical excision and there was no recurrence after a mean post-treatment period of 34.5 months. The findings were compared with 450 cases of oral lipomas reported in the literature. Lipomas continue to be an uncommon neoplasm of the oral cavity. Radiography is a valuable tool due to the possible occurrence of bone involvement. Surgical excision is the treatment of choice and recurrence is not expected.
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              Angiolipoma of the esophagus: a rare clinical dilemma.

              Benign tumors of the esophagus are a rare but diverse group of lesions. Although non-malignant in biology, their presence can cause significant morbidity, including dysphagia, bleeding, gastrointestinal obstruction, and even asphyxiation. Diagnosis is frequently made using radiographic and endoscopic means, even in the absence of definitive biopsy. If discovered early, endoscopic or minimally invasive techniques may be used to excise these lesions, with essentially 100% cure rates. However, if discovered late, open excision or even esophagectomy may be required. Angiolipoma represents perhaps one of the rarest of the benign entities to affect the esophagus, with only a few cases reported in the current literature. We present the case of an 85-year-old man who developed complete esophageal obstruction due to a large, pedunculated angiolipoma, requiring open surgical excision.
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                Author and article information

                Contributors
                Journal
                Gastroenterol Res Pract
                Gastroenterol Res Pract
                GRP
                Gastroenterology Research and Practice
                Hindawi
                1687-6121
                1687-630X
                2020
                14 February 2020
                : 2020
                : 3581267
                Affiliations
                1Department of Gastroenterology, The Fourth Affiliated Hospital of China Medical University, Shenyang, 110000 Liaoning Province, China
                2Department of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, 121001 Liaoning Province, China
                Author notes

                Academic Editor: Jose Celso Ardengh

                Author information
                https://orcid.org/0000-0003-4513-016X
                https://orcid.org/0000-0001-7619-4620
                https://orcid.org/0000-0002-5037-1462
                https://orcid.org/0000-0003-1106-8783
                https://orcid.org/0000-0003-2022-9075
                https://orcid.org/0000-0001-9450-6288
                https://orcid.org/0000-0001-9741-1444
                https://orcid.org/0000-0002-0221-7284
                https://orcid.org/0000-0002-3127-3824
                https://orcid.org/0000-0002-9208-9326
                https://orcid.org/0000-0002-6856-7199
                https://orcid.org/0000-0001-8620-2903
                https://orcid.org/0000-0002-6830-767X
                https://orcid.org/0000-0002-4276-8304
                https://orcid.org/0000-0001-5374-1521
                https://orcid.org/0000-0002-9918-6858
                https://orcid.org/0000-0003-1832-3134
                https://orcid.org/0000-0001-6428-4581
                https://orcid.org/0000-0002-1379-3818
                Article
                10.1155/2020/3581267
                7042500
                32148476
                21085623-264e-4311-8483-972588c2a2cd
                Copyright © 2020 Lu Liu et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 4 December 2019
                : 7 January 2020
                Categories
                Research Article

                Gastroenterology & Hepatology
                Gastroenterology & Hepatology

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