Accuracy of LightCycler(®) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis.

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Abstract

There is an urgent need to develop diagnostic tests to improve the detection of pathogens causing life-threatening infection (sepsis). SeptiFast is a CE-marked multi-pathogen real-time PCR system capable of detecting DNA sequences of bacteria and fungi present in blood samples within a few hours. We report here a systematic review and meta-analysis of diagnostic accuracy studies of SeptiFast in the setting of suspected sepsis.

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Journal

Journal ID (iso-abbrev): Intensive Care Med

Title: Intensive care medicine

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1432-1238

ISSN (Print): 0342-4642

Publication date (Electronic): Jan 2015

Volume: 41

Issue: 1

Affiliations

[1 ] Infection, Injury and Inflammation Research Group, Biomedical Facility, Clinical Sciences, Manchester Academic Health Sciences Centre, Salford Royal NHS Foundation Trust, Salford, Greater Manchester, M6 8HD, UK, paul.m.dark@manchester.ac.uk.

Article

DOI: 10.1007/s00134-014-3553-8

PubMed ID: 25416643

SO-VID: 1f54b949-7d03-4373-9e7e-1eba4030466e

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