Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study.

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Abstract

There is a need to develop and validate surrogate markers of cardiovascular disease (CVD) in subjects with diabetes. The macrovascular changes associated with diabetes include aggravated atherosclerosis, increased arterial stiffness and endothelial dysfunction. The aim of this study was to determine which of these factors is most strongly associated with clinically manifest cardiovascular events.

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Journal

Journal ID (iso-abbrev): J. Intern. Med.

Title: Journal of internal medicine

Publisher: Wiley-Blackwell

ISSN (Electronic): 1365-2796

ISSN (Print): 0954-6820

Publication date (Electronic): Sep 2015

Volume: 278

Issue: 3

Affiliations

[1 ] Diabetes and Vascular Medicine, University of Exeter Medical School and NIHR Exeter Clinical Research Facility, Exeter, UK.

[2 ] Medical Research Institute, University of Dundee, Dundee, UK.

[3 ] Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

[4 ] Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa, Pisa, Italy.

[5 ] Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.

Article

DOI: 10.1111/joim.12359

PubMed ID: 25752315

SO-VID: 1f3dcd07-5485-48ea-baef-dac0a62dd222

History

Keywords: cardiovascular disease,diabetes mellitus,risk factors,vasculature

Data availability:

Keywords: cardiovascular disease, diabetes mellitus, risk factors, vasculature

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