Metadherin (MTDH) overexpression significantly correlates with advanced tumor grade and stages among colorectal cancer patients.

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Abstract

Colorectal cancer is the 4th leading cause of cancer related deaths affecting both men and women worldwide. In the present study, any probable role of MTDH mRNA expression in CRC tumorigenesis was explored using both discovery and validation cohorts.

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Author and article information

Journal

Journal ID (iso-abbrev): Mol Biol Rep

Title: Molecular biology reports

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1573-4978

ISSN (Print): 0301-4851

Publication date (Electronic): Dec 2021

Volume: 48

Issue: 12

Affiliations

[1 ] Department of Biosciences, COMSATS University Islamabad, Park Road, Islamabad, Pakistan.

[2 ] College of Medicine, University of Nebraska, Medical Center, Omaha, USA.

[3 ] Department of Molecular Biology, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan.

[4 ] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.

[5 ] Department of General Surgery, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan.

[6 ] Department of Biosciences, COMSATS University Islamabad, Park Road, Islamabad, Pakistan. famalik@comsats.edu.pk.

Article

Publisher Item ID: 10.1007/s11033-021-06834-8

DOI: 10.1007/s11033-021-06834-8

PubMed ID: 34741710

SO-VID: 1f24d06a-044e-4c6a-b66c-01c48a9ca9ac

History

Keywords: Oncogenes,MTDH,Expression analysis,Colorectal cancer,BRB array

Data availability:

Keywords: Oncogenes, MTDH, Expression analysis, Colorectal cancer, BRB array

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