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      Implementation and optimization of molecular rapid diagnostic tests for bloodstream infections

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          Most cited references54

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          Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship.

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            Randomized Trial of Rapid Multiplex Polymerase Chain Reaction-Based Blood Culture Identification and Susceptibility Testing.

            The value of rapid, panel-based molecular diagnostics for positive blood culture bottles (BCBs) has not been rigorously assessed. We performed a prospective randomized controlled trial evaluating outcomes associated with rapid multiplex PCR (rmPCR) detection of bacteria, fungi, and resistance genes directly from positive BCBs.
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              The Effect of Molecular Rapid Diagnostic Testing on Clinical Outcomes in Bloodstream Infections: A Systematic Review and Meta-analysis.

               Previous reports on molecular rapid diagnostic testing (mRDT) do not consistently demonstrate improved clinical outcomes in bloodstream infections (BSIs). This meta-analysis seeks to evaluate the impact of mRDT in improving clinical outcomes in BSIs.
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                Author and article information

                Journal
                American Journal of Health-System Pharmacy
                Oxford University Press (OUP)
                1079-2082
                1535-2900
                August 15 2018
                August 15 2018
                August 15 2018
                August 15 2018
                : 75
                : 16
                : 1191-1202
                Affiliations
                [1 ]College of Pharmacy, University of Illinois at Chicago, Chicago, IL.
                [2 ]Department of Pharmacy, University of Utah, Salt Lake City, UT.
                [3 ]Department of Pharmacy, Grady Health System, Atlanta, GA.
                [4 ]Department of Antibiotic Stewardship, St. Anthony Hospital, Oklahoma City, OK.
                [5 ]Department of Pharmacy and Division of Infectious Diseases, Medical University of South Carolina, Charleston, SC.
                Article
                10.2146/ajhp170604
                29970407
                1d7cc74e-a4c7-4cc7-bd8c-27fce6e02a67
                © 2018
                History

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