Biomarkers for severity of neonatal hypoxic-ischemic encephalopathy and outcomes in newborns receiving hypothermia therapy.

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Abstract

To evaluate serum neuronal and inflammatory biomarkers to determine whether measurements of umbilical cords at birth can stratify severity of hypoxic-ischemic encephalopathy (HIE), whether serial measurements differ with hypothermia-rewarming, and whether biomarkers correlate with neurological outcomes.

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Author and article information

Journal

Journal ID (iso-abbrev): J Pediatr

Title: The Journal of pediatrics

Publisher: Elsevier BV

ISSN (Electronic): 1097-6833

ISSN (Print): 0022-3476

Publication date (Electronic): Mar 2014

Volume: 164

Issue: 3

Affiliations

[1 ] Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address: lina.chalak@utsouthwestern.edu.

[2 ] Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX.

[3 ] Department of Clinical Sciences and Statistics, University of Texas Southwestern Medical Center, Dallas, TX.

[4 ] Department of Pediatrics, Brown University, Women & Infants Hospital of Rhode Island, Providence, RI.

Article

Mid ID: NIHMS575017 Publisher Item ID: S0022-3476(13)01363-2

DOI: 10.1016/j.jpeds.2013.10.067

PMC ID: 4006934

PubMed ID: 24332821

SO-VID: 1d094fb7-69b2-4f8e-9a4a-c52e1a86b3e3

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