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      No Little Feet: Managing Pseudocyesis in a Homeless, Acutely Manic Patient with Schizoaffective Disorder, Bipolar Type

      case-report
      1 , , 2 , 3 , 4
      Case Reports in Psychiatry
      Hindawi

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          Abstract

          Pseudocyesis is a complex psychiatric manifestation of the physical symptoms of pregnancy. Although not pregnant, the pseudocyetic patient displays signs and symptoms consistent with pregnancy, such as abdominal distention, cramping, and/or sensations of fetal movement. Pseudocyesis is more common in developing countries than in the developed world, possibly due to the importance that traditional societies attach to childbearing and the low social status that these societies assign to women who are unable to produce children. Socioeconomically disadvantaged women in developed countries may also be at increased risk. Although the etiology, pathogenesis, diagnosis, and management of pseudocyesis are poorly understood, it manifests with real symptoms, which may complicate both the patient's perspective about her condition and the medical and psychiatric teams' approach to the patient. This case report is one of only a few in the literature to present an example of pseudocyesis developing in the context of acute mania. After describing the patient's clinical course, from her initial symptoms of pseudocyesis to their eventual resolution, this report will provide recommendations for the sensitive care of patients with this rare but significant condition.

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          Most cited references19

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          Diagnostic and statistical manual of mental disorders

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            A safety evaluation of aripiprazole in the treatment of schizophrenia.

            Aripiprazole is a third generation antipsychotic approved by the US Food and Drug Administration (FDA) for the treatment of schizophrenia. Aripiprazole is available as oral and long-acting injectable (LAI) depot formulations, with a unique mechanism of action comprising partial D2 and serotonin 5-HT1A agonism and antagonism at serotonin 5-HT2A receptors.
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              Assessment of Neuroendocrine Changes and Hypothalamo-Pituitary Autoimmunity in Patients with COVID-19

              SARS-CoV-2 may affect the hypothalamic-pituitary axis and pituitary dysfunction may occur. Therefore, we investigated neuroendocrine changes, in particular, secondary adrenal insufficiency, using a dynamic test and the role of autoimmunity in pituitary dysfunction in patients with COVID-19. The single-center, prospective, case-control study included patients with polymerase chain reaction (PCR)-confirmed COVID-19 and healthy controls. Basal hormone levels were measured, and the adrenocorticotropic hormone (ACTH) stimulation test was performed. Antipituitary (APA) and antihypothalamic antibodies (AHA) were also determined. We examined a total of 49 patients with COVID-19 and 28 healthy controls. The frequency of adrenal insufficiency in patients with COVID-19 was found as 8.2%. Patients with COVID-19 had lower free T3, IGF-1, and total testosterone levels, and higher cortisol and prolactin levels when compared with controls. We also demonstrated the presence of APA in three and AHA in one of four patients with adrenal insufficiency. In conclusion, COVID-19 may result in adrenal insufficiency, thus routine screening of adrenal functions in these patients is needed. Endocrine disturbances in COVID-19 are similar to those seen in acute stressful conditions or infections. Pituitary or hypothalamic autoimmunity may play a role in neuroendocrine abnormalities in COVID-19.
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                Author and article information

                Contributors
                Journal
                Case Rep Psychiatry
                Case Rep Psychiatry
                CRIPS
                Case Reports in Psychiatry
                Hindawi
                2090-682X
                2090-6838
                2023
                13 December 2023
                : 2023
                : 2504871
                Affiliations
                1Department of Psychiatry, Ocean University Medical Center, 1610 Route 88, Brick, NJ 08724, USA
                2Forensic Psychiatry, Emory University, 12 Executive Park Dr. NE, Atlanta, GA 30329, USA
                3Department of Psychiatry, Hackensack Meridian School of Medicine, 340 Kingsland St., Nutley, NJ 07110, USA
                4Department of Psychiatry, Raritan Bay Medical Center, 530 New Brunswick Ave., Perth Amboy, NJ 08861, USA
                Author notes

                Academic Editor: Lut Tamam

                Author information
                https://orcid.org/0009-0000-1225-6677
                https://orcid.org/0009-0003-2234-9238
                https://orcid.org/0009-0008-3813-5513
                https://orcid.org/0009-0001-2946-1228
                Article
                10.1155/2023/2504871
                10733053
                38125275
                1be7b67c-9f2f-4032-8c7f-e49a5a900e7f
                Copyright © 2023 Talitha West et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 19 October 2023
                : 25 November 2023
                : 29 November 2023
                Categories
                Case Report

                Clinical Psychology & Psychiatry
                Clinical Psychology & Psychiatry

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