Protective effect of oroxylin A against lipopolysaccharide and/or D-galactosamine-induced acute liver injury in mice.

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Abstract

Oroxylin A, a natural flavonoid isolated from Scutellariae baicalensis, has been reported to possess a wide spectrum of pharmacologic activities. However, the effects of oroxylin A on liver injury are poor understood. The purpose of this study was to investigate the effects of oroxylin A on acute liver injury in mice induced by lipopolysaccharide and/or D-galactosamine (LPS and/or D-GalN).

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Author and article information

Journal

Journal ID (iso-abbrev): J. Surg. Res.

Title: The Journal of surgical research

Publisher: Elsevier BV

ISSN (Electronic): 1095-8673

ISSN (Print): 0022-4804

Publication date (Electronic): May 15 2015

Volume: 195

Issue: 2

Affiliations

[1 ] Department of Infectious Diseases, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.

[2 ] Department of Infectious Diseases, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. Electronic address: lijingyuanlb@163.com.

Article

Publisher Item ID: S0022-4804(15)00076-1

DOI: 10.1016/j.jss.2015.01.047

PubMed ID: 25818981

SO-VID: 1af771d7-a72f-4721-9471-640708a3520a

History

Keywords: LPS,NF-κB,Nrf2,Oroxylin A,TLR4

Data availability:

Keywords: LPS, NF-κB, Nrf2, Oroxylin A, TLR4

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