Role of Allogeneic Hematopoietic Stem Cell Transplant for Chronic Granulomatous Disease (CGD): a Report of the United States Immunodeficiency Network.

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Abstract

Chronic granulomatous disease (CGD) is a primary immunodeficiency for which allogeneic hematopoietic stem cell transplant (HSCT) offers potential cure. Direct comparison of HSCT to non-HSCT management in the North American population was performed to identify clinical factors associated with overall survival (OS) and transplant-related survival (TRS).

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Journal

Journal ID (iso-abbrev): J Clin Immunol

Title: Journal of clinical immunology

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1573-2592

ISSN (Print): 0271-9142

Publication date (Electronic): May 2019

Volume: 39

Issue: 4

Affiliations

[1 ] Cleveland Medical Center, Department of Pediatric Hematology-Oncology, Rainbow Babies and Children's Hospital, 11100 Euclid Ave., Cleveland, OH, 44106, USA.

[2 ] Department of Population and Quantitative Health Sciences, Case Western Reserve University, Wood Bldg., Rm. WG-82P, 2109 Adelbert Rd., Cleveland, OH, 44106, USA.

[3 ] National Institutes of Health, National Human Genome Research Institute, Bldg. 10/10C-103, MSC 1611, 10 Center Dr., Bethesda, MD, 20892, USA.

[4 ] Cleveland Medical Center, Department of Pediatric Hematology-Oncology, Rainbow Babies and Children's Hospital, 11100 Euclid Ave., Cleveland, OH, 44106, USA. Jignesh.Dalal@UHhospitals.org.

Article

Publisher Item ID: 10.1007/s10875-019-00635-2

DOI: 10.1007/s10875-019-00635-2

PubMed ID: 31111420

SO-VID: 1ad8d1e0-f33a-42d3-a2c7-2b10c92207e4

History

Keywords: Chronic granulomatous disease,USIDNET,graft-versus-host disease,hematopoietic stem cell transplant,overall survival,primary immunodeficiency

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Keywords: Chronic granulomatous disease, USIDNET, graft-versus-host disease, hematopoietic stem cell transplant, overall survival, primary immunodeficiency

Role of Allogeneic Hematopoietic Stem Cell Transplant for Chronic Granulomatous Disease (CGD): a Report of the United States Immunodeficiency Network.

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