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Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses.

Author(s): William W. Du, Weining Yang, Yu Chen, Zhong-Kai Wu, Francis Stuart Foster, Zhenguo Yang, Xiangmin Li, Burton Yang

Publication date: 2017-05-07

Journal: European Heart Journal

Publisher: Oxford University Press (OUP)

Keywords: Heart senescence, Foxo3, Circular RNA, Stress response

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Abstract

Circular RNAs are a subclass of non-coding RNAs detected within mammalian cells. This study was designed to test the roles of a circular RNA circ-Foxo3 in senescence using in vitro and in vivo approaches.

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PubMed ID:: 26873092

DOI:: 10.1093/eurheartj/ehw001

Keywords: Heart senescence,Foxo3,Circular RNA,Stress response

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Keywords: Heart senescence, Foxo3, Circular RNA, Stress response

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