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      Rituximab-CHOP versus CHOP alone or with maintenance rituximab in older patients with diffuse large B-cell lymphoma.

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          Abstract

          To address early and late treatment failures in older patients with diffuse large B-cell lymphoma (DLBCL), we designed a two-stage randomized trial of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) versus rituximab plus CHOP (R-CHOP), with a second random assignment to maintenance rituximab (MR) or observation in responding patients.

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          Author and article information

          Journal
          J Clin Oncol
          Journal of clinical oncology : official journal of the American Society of Clinical Oncology
          American Society of Clinical Oncology (ASCO)
          1527-7755
          0732-183X
          Jul 01 2006
          : 24
          : 19
          Affiliations
          [1 ] Division of Hematology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA. habermann.thomas@mayo.edu
          Article
          JCO.2005.05.1003
          10.1200/JCO.2005.05.1003
          16754935
          1a7e18a1-855d-40d4-8208-ff9adaaba062
          History

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