Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

BRCA1 and BRCA2 mutations in general populations and in various types of cancers have not been well characterized. We investigated the presence of these mutations in unselected patients with newly diagnosed incident ovarian cancer in Ontario, Canada, with respect to cancers reported among their relatives.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): J Natl Cancer Inst

Title: Journal of the National Cancer Institute

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1460-2105

ISSN (Print): 0027-8874

Publication date (Electronic): Dec 06 2006

Volume: 98

Issue: 23

Affiliations

[1 ] Department of Epidemiology and Public Health, Yale University School of Medicine, 60 College St., PO Box 208034, New Haven, CT 06520-8034, USA. harvey.risch@yale.edu

Article

Publisher Item ID: 98/23/1694

DOI: 10.1093/jnci/djj465

PubMed ID: 17148771

SO-VID: 1a26bd4f-46f4-4db0-87f0-5461ad18b4e8

History

Data availability:

Comments

Comment on this article

scite_

Smart Citations

Citing PublicationsSupportingMentioningContrasting

View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.