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      A third transition in science?

      research-article
      1 , 2 , 3 ,
      Interface Focus
      The Royal Society
      Newtonian paradigm, affordances, set theory, indefinite uses of X, constraint closure, emergent creativity of the biosphere

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          Abstract

          Since Newton, classical and quantum physics depend upon the ‘Newtonian paradigm’. The relevant variables of the system are identified. For example, we identify the position and momentum of classical particles. Laws of motion in differential form connecting the variables are formulated. An example is Newton’s three laws of motion. The boundary conditions creating the phase space of all possible values of the variables are defined. Then, given any initial condition, the differential equations of motion are integrated to yield an entailed trajectory in the prestated phase space. It is fundamental to the Newtonian paradigm that the set of possibilities that constitute the phase space is always definable and fixed ahead of time. This fails for the diachronic evolution of ever-new adaptations in any biosphere. Living cells achieve constraint closure and construct themselves. Thus, living cells, evolving via heritable variation and natural selection, adaptively construct new-in-the-universe possibilities. We can neither define nor deduce the evolving phase space: we can use no mathematics based on set theory to do so. We cannot write or solve differential equations for the diachronic evolution of ever-new adaptations in a biosphere. Evolving biospheres are outside the Newtonian paradigm. There can be no theory of everything that entails all that comes to exist. We face a third major transition in science beyond the Pythagorean dream that ‘all is number’ echoed by Newtonian physics. However, we begin to understand the emergent creativity of an evolving biosphere: emergence is not engineering.

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          �ber den anschaulichen Inhalt der quantentheoretischen Kinematik und Mechanik

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            Exaptation—a Missing Term in the Science of Form

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                Author and article information

                Contributors
                Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: Writing – original draftRole: Writing – review & editing
                Role: InvestigationRole: Writing – original draftRole: Writing – review & editing
                Journal
                Interface Focus
                Interface Focus
                RSFS
                royfocus
                Interface Focus
                The Royal Society
                2042-8898
                2042-8901
                April 14, 2023
                6 June 2023
                April 14, 2023
                : 13
                : 3 , Theme issue ‘Making and breaking symmetries in mind and life’ organised by Adam Safron, Michael Levin, Adeel Razi, Zahra Sheikhbahaee, Dalton Sakthivadivel and Magnus Bein
                : 20220063
                Affiliations
                [ 1 ] Institute for Systems Biology, , Seattle, WA, USA
                [ 2 ] Department of Computer Science and Engineering, Università di Bologna, , Campus of Cesena, Cesena, Italy
                [ 3 ] European Centre for Living Technology, , Venezia, Italy
                Author notes

                One contribution of 15 to a theme issue ‘ Making and breaking symmetries in mind and life’.

                Author information
                http://orcid.org/0000-0001-7094-4312
                http://orcid.org/0000-0001-9891-5441
                Article
                rsfs20220063
                10.1098/rsfs.2022.0063
                10102722
                37065266
                19d76a0d-0605-4b58-8064-c690241f3beb
                © 2023 The Authors.

                Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

                History
                : October 25, 2022
                : January 17, 2023
                Categories
                1004
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                Life sciences
                newtonian paradigm,affordances,set theory,indefinite uses of x,constraint closure,emergent creativity of the biosphere

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