0
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Doxycycline Drug Release Property of Glutaraldehyde Crosslinked Hydrogel

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          A BSTRACT

          Delayed wound healing is one of the most common problems associated with diabetic patients. There are several factors associated with delayed wound healing. It has been observed that if not cured the wound healing takes a long time. This is the reason that researchers are engaged in developing sustainable, biodegradable, biocompatible, and effective wound-healing dressings. However, it has been observed that the traditional wound-healing bandages have drawbacks such as allergies and less efficiency in the absorption of wound exudate. To fill the gap, hydrogels have been developed recently which have higher absorption capacity. In addition, they pose slow drug release properties. Therefore, the present study was conducted to prepare an effective and promising hydrogel that has high drug absorption and release properties.

          Related collections

          Most cited references6

          • Record: found
          • Abstract: not found
          • Article: not found

          Recent advances in novel drug delivery systems and approaches for management of breast cancer: A comprehensive review

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Chitosan crosslinking with a vanillin isomer toward self-healing hydrogels with antifungal activity.

            The purpose of the study was to develop new antimicrobial hydrogels from natural resources that may promote wound healing and prevent bacterial skin infection. The new hydrogels were synthesized by crosslinking chitosan with a vanillin isomer, 5-methoxysalicylaldehyde, by a friendly and easy method. To characterize these hydrogels, their structural and morphological properties were explored by FTIR, 1H NMR, SEM, POM, and TGA. In view of the targeted application, swelling behavior, biodegradability, antimicrobial activity and biocompatibility were investigated in vitro. Structural and morphological studies confirmed the formation of new hydrogels via the imination reaction concomitant with the supramolecular organization. The hydrogels were highly porous with the average pore diameter around 80 μm, and a swelling rate controlled by the crosslinking density and medium pH. The hydrogels showed a progressive weight loss in the presence of lysozyme up to 35%, during 21 days of testing. They proved non-cytotoxic effect on Normal Human Dermal Fibroblasts using MTS test and powerful antifungal activity against Candida Albicans, as determined by disk diffusion assay. All these properties indicate the new hydrogels as a promising option for the treatment of various skin lesions.
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              A comprehensive review on biodegradable polylactic acid polymer matrix composite material reinforced with synthetic and natural fibers

                Bookmark

                Author and article information

                Journal
                J Pharm Bioallied Sci
                J Pharm Bioallied Sci
                JPBS
                J Pharm Bioall Sci
                Journal of Pharmacy & Bioallied Sciences
                Wolters Kluwer - Medknow (India )
                0976-4879
                0975-7406
                April 2024
                16 April 2024
                : 16
                : Suppl 2
                : S1204-S1206
                Affiliations
                [1 ]Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, Tamil Nadu, India
                [2 ]Department of Bioengineering, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, Tamil Nadu, India
                Author notes
                Address for correspondence: Dr. Vinay Kumar, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam - 602 105, Chennai, Tamil Nadu, India. E-mail: vinaykumar.smc@ 123456saveetha.com
                Article
                JPBS-16-1204
                10.4103/jpbs.jpbs_541_23
                11174209
                189a1091-ea82-4a0a-b0b9-ef8cd9a75c1e
                Copyright: © 2024 Journal of Pharmacy and Bioallied Sciences

                This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

                History
                : 09 August 2023
                : 20 October 2023
                : 22 October 2023
                Categories
                Original Article

                Pharmacology & Pharmaceutical medicine
                amoxycillin,crosslinking,drug release,good health and well-being,life on land

                Comments

                Comment on this article