Contributors
Arun Rajaratnam: Role: Data curationRole: Formal analysisRole: Writing – original draftRole: Writing
– review & editing
Sofiya Rehman: Role: Data curationRole: Formal analysisRole: InvestigationRole: Writing – original
draftRole: Writing – review & editing
Prerna Sharma: Role: Data curationRole: Formal analysisRole: InvestigationRole: Writing – review
& editing
Vikas K. Singh: Role: Data curationRole: InvestigationRole: Writing – review & editing
Melissa Saul:
ORCID: https://orcid.org/0000-0002-6712-5102
Role: Data curationRole: MethodologyRole: Writing – review & editing
Rebecca R. Vanderpool: Role: MethodologyRole: SoftwareRole: SupervisionRole: Writing – review & editing
Mark T. Gladwin: Role: Writing – review & editing
Marc A. Simon:
ORCID: https://orcid.org/0000-0003-3080-3675
Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
Project administrationRole: ResourcesRole: SoftwareRole: SupervisionRole: ValidationRole:
VisualizationRole: Writing – original draftRole: Writing – review & editing
Alison Morris: Role: ConceptualizationRole: Data curationRole: Funding acquisitionRole: InvestigationRole:
MethodologyRole: Project administrationRole: ResourcesRole: SupervisionRole: Writing
– original draftRole: Writing – review & editing
James West: Role: Editor
Journal
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS One
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
23
February
2021
Publication date Collection: 2021
Volume: 16
Issue: 2
Electronic Location Identifier: e0243274
Affiliations
[1
]
Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh,
Pittsburgh, PA, United States of America
[2
]
Department of Medicine, University of Pittsburgh, Pittsburgh, PA United States of
America
[3
]
Analytics Center, University of Pittsburgh, Pittsburgh, PA, United States of America
[4
]
Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States
of America
[5
]
Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh,
Pittsburgh, PA, United States of America
[6
]
Division of Cardiology, University of Pittsburgh, Pittsburgh, PA, United States of
America
[7
]
UPMC Heart and Vascular Institute, Pittsburgh, PA, United States of America
Vanderbilt University Medical Center, UNITED STATES
Author notes
Competing Interests: The authors have read the journal’s policy, and the authors of the study have the
following competing interests to declare: Outside of the present study, MAS received
research support from Novartis and Aadi and consultancy fees from Complexa, Actelion,
United Therapeutics. AM received support for this study in the form of a grant (number
IN-US-300-4452) from Gilead. There are no patents, products in development or marketed
products associated with this research to declare. This does not alter our adherence
to PLOS ONE policies on sharing data and materials.
Author information
Article
Publisher ID:
PONE-D-20-02369
DOI: 10.1371/journal.pone.0243274
PMC ID: 7901734
PubMed ID: 33621231
SO-VID: 180fe4f9-11c4-48bf-8cbc-de8e142a42f6
Copyright © © 2021 Rajaratnam et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 26
January
2020
Date
accepted
: 18
November
2020
Page count
Figures: 1,
Tables: 4,
Pages: 12
Funding
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: 2P01HL103455
Award Recipient
:
ORCID: https://orcid.org/0000-0003-3080-3675
Marc A. Simon
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: 2P01HL103455
Award Recipient
:
Mark T. Gladwin
Funded by: National Institutes of Health (US)
Award ID: 2P01HL103455
Award Recipient
:
Alison Morris
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: R01HL098032
Award Recipient
:
Mark T. Gladwin
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: R01HL096973
Award Recipient
:
Mark T. Gladwin
Funded by: National Institutes of Health (US)
Award ID: 1R01AG058659
Award Recipient
:
ORCID: https://orcid.org/0000-0003-3080-3675
Marc A. Simon
Funded by: National Institutes of Health (US)
Award ID: K24123342
Award Recipient
:
Alison Morris
Funded by: Gilead Sciences (US)
Award ID: IN-US-300-4452
Award Recipient
:
Alison Morris
This work supported in part by the NIH grants NIH 2P01HL103455 (MAS, MTG, AM), R01HL098032
(MTG), RO1HL096973 (MTG), 1R01AG058659 (MAS), K24123342 (AM) and Gilead (award number
IN-US-300-4452, awarded to AM). The funders had no role in study design, data collection
and analysis, decision to publish, or preparation of the manuscript.
Categories
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Pulmonology
Subject:
Pulmonary Hypertension
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Blood Vessels
Subject:
Arteries
Subject:
Pulmonary Arteries
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Blood Vessels
Subject:
Arteries
Subject:
Pulmonary Arteries
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Viral Pathogens
Subject:
Immunodeficiency Viruses
Subject:
HIV
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Viral Pathogens
Subject:
Immunodeficiency Viruses
Subject:
HIV
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral Pathogens
Subject:
Immunodeficiency Viruses
Subject:
HIV
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Immunodeficiency Viruses
Subject:
HIV
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
RNA viruses
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
HIV
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Viral Pathogens
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
HIV
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Viral Pathogens
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
HIV
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral Pathogens
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
HIV
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Virology
Subject:
Viral Transmission and Infection
Subject:
Viral Load
Subject:
Medicine and health sciences
Subject:
Diagnostic medicine
Subject:
HIV diagnosis and management
Subject:
Medicine and Health Sciences
Subject:
Vascular Medicine
Subject:
Blood Pressure
Subject:
Systolic Pressure
Subject:
Medicine and Health Sciences
Subject:
Hematology
Subject:
Hemodynamics
Subject:
Medicine and Health Sciences
Subject:
Vascular Medicine
Subject:
Blood Pressure
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