The Influence of Cervicovaginal Microbiota on Mucosal Immunity and Prophylaxis in the Battle against HIV.

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Abstract

Young women in sub-Saharan Africa bear a disproportionate burden of the global HIV epidemic. In this review, we examine how cervicovaginal microbiota modulate structural and immune defenses in the female genital tract and influence HIV susceptibility.

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Journal

Journal ID (iso-abbrev): Curr HIV/AIDS Rep

Title: Current HIV/AIDS reports

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1548-3576

ISSN (Print): 1548-3568

Publication date (Electronic): February 2018

Volume: 15

Issue: 1

Affiliations

[1 ] Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, 400 Technology Square, Cambridge, MA, 02139, USA.

[2 ] Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, 02115, USA.

[3 ] Harvard Medical School, Boston, MA, 02115, USA.

[4 ] Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, 400 Technology Square, Cambridge, MA, 02139, USA. dkwon@mgh.harvard.edu.

[5 ] Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, 02115, USA. dkwon@mgh.harvard.edu.

[6 ] Harvard Medical School, Boston, MA, 02115, USA. dkwon@mgh.harvard.edu.

Article

Publisher Item ID: 10.1007/s11904-018-0380-5

DOI: 10.1007/s11904-018-0380-5

PubMed ID: 29516267

SO-VID: 173cfa38-b9d9-4c05-aa3e-5dfeb1b6e573

History

Keywords: Pre-exposure prophylaxis (PrEP),Cervicovaginal microbiome,Genital inflammation,HIV/AIDS

Data availability:

Keywords: Pre-exposure prophylaxis (PrEP), Cervicovaginal microbiome, Genital inflammation, HIV/AIDS

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