This trial was designed to compare the incidence of delayed postprocedural pain after administration of iopentol (Imagopaque, Nycomed Imaging AS, Oslo, Norway) 300 mg I/ml versus ioxaglate (Hexabrix, Guerbet, Aulnay-sous-Bois, France) 320 mg I/ml in single-contrast knee arthrography. Other adverse events and radiographic efficacy were also evaluated.