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The prognostic role of sex, race, and human papillomavirus in oropharyngeal and nonoropharyngeal head and neck squamous cell cancer.
Carole Fakhry
1 ,
William H Westra
2 ,
Steven J Wang
3 ,
Annemieke van Zante
4 ,
Yuehan Zhang
5 ,
Eleni Rettig
1 ,
Linda X Yin
1 ,
William R Ryan
3 ,
Patrick K Ha
3 ,
Alicia Wentz
5 ,
Wayne Koch
1 ,
Jeremy D Richmon
1 ,
David W Eisele
1 ,
Gypsyamber D'Souza
5
May 01 2017
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Abstract
Human papillomavirus (HPV) is a well-established prognostic marker for oropharyngeal squamous cell cancer (OPSCC). Because of the limited numbers of women and nonwhites in studies to date, sex and racial/ethnic differences in prognosis have not been well explored. In this study, survival differences were explored by the tumor HPV status among 1) patients with OPSCCs by sex and race and 2) patients with nonoropharyngeal (non-OP) head and neck squamous cell cancers (HNSCCs).