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      Manejo endoscópico de papiloma invertido nasosinusal: Experiencia de 15 años en Hospital Clínico Regional de Concepción Translated title: Endoscopic management of sinonasal inverted papilloma: 15 years experience in Concepción Clinical Hospital

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          Abstract

          Introducción: El papiloma invertido es uno de los tumores benignos más frecuentes de la región nasosinusal. Los principales problemas en su manejo son la recurrencia y transformación maligna. Su tratamiento es la extirpación quirúrgica. Objetivos: Describir y analizar las caracterfsticas cínicas y epidemiológicas, así como el resultado del tratamiento endoscópico practicado en el Hospital Clínico Regional de Concepción. Material y método: Se realizó un estudio retrospectivo, descriptivo, de todos los pacientes con diagnóstico de papiloma invertido nasosinusal operados vfa abordaje endoscópico entre los años 1997 y 2012. Se analizaron variables epidemiológicas y clínicas, incluyendo análisis de las recurrencias y transformación/asociación a cáncer. Resultados: Se encontraron 57 casos de papiloma invertido nasosinusal, 55 de los cuales se abordaron endoscópicamente, 65,5% hombres, 54,7 años en promedio de edad. La obstrucción nasal fue el principal síntoma. La mayor cantidad se concentró en estadio 2 (47,3%) y 3 (32,7%) de Krouse. Complicaciones relevantes 7,8%, las cuales fueron resueltas sin secuelas. Seguimiento promedio de 4,1 años, con una recurrencia de 5 (9,1%) casos, una persistencia (1,8%). Asociación con carcinoma escamoso en el 5,5% de los casos. Conclusión: La experiencia con la resección endoscópica en el papiloma invertido nasosinusal ha demostrado ser efectiva en nuestro medio, con baja tasa de complicaciones y recurrencias.

          Translated abstract

          Introduction: The inverted papilloma is one of the most common benign tumors of the sinonasal region. The main problems in their management are the recurrence and malignant transformation. Their treatment is surgical removal. Aim: To describe and analyze the clinical and epidemiological characteristics, as well as the results of endoscopic treatment in a tertiary hospital. Materials and methods: A retrospective, descriptive study of all patients with diagnosis ofsinonasal inverted papilloma operated by endoscopic approach between 1997 and 2012 was carried out. Epidemiological and clinical variables were analyzed, including analysis of recurrences and transformation to / association with cancer. Results: 57 cases of sinonasal inverted papilloma were found, 55 of which were endoscopically resected, 65.5% male, 54.7 years old on average. Nasal obstruction was the main symptom. Most of them were in Krouse stage 2 (47.3%) and 3 (32.7%); 7.8% of major complications, which were resolved without sequels. The follow up average was 4.11 years, with a recurrence of 5 (9.1%) cases, and (1.8%) persistence. Association with squamous-cell carcinoma was found in 5.5% of cases. Conclusion: The clinical and epidemiological characteristics do not differ greatly from those reported in the literature. Experience with endoscopic resection in sinonasal inverted papilloma has proven effective in our clinical practice, with a low rate of complications and recurrences, this approach currently being the first choice in most cases.

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          Most cited references19

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          Development of a staging system for inverted papilloma.

          Inverted papillomas of the nose and sinuses are uncommon neoplasms. In the past decade there has been a trend toward the use of endoscopic surgical techniques in the management of these tumors, in contrast to the extensive open procedures recommended previously. This trend has not been without controversy, given the association of inverted papillomas with malignancy. It has been difficult to compare surgical approaches to these neoplasms, because of the absence of a uniformly applied staging system representing the extent of disease. It was the purpose of this study to develop such a system that could be easily applied in outcomes research. This study involved an integrated literature review and a synthesis of findings from a number of studies. Previous and current clinical studies examining the treatment of inverted papilloma were reviewed. Findings were organized, and a staging system was framed based on this review. A simple, easily applied staging system was developed based on the extent of tumor involvement noted on endoscopic examination of the nasal cavity and computed tomography (CT) scan evaluation. Stage I disease is limited to the nasal cavity alone. Stage II disease is limited to the ethmoid sinuses and medial and superior portions of the maxillary sinuses. Stage III disease involves the lateral or inferior aspects of the maxillary sinuses or extension into the frontal or sphenoid sinuses. Stage IV disease involves tumor spread outside the confines of the nose and sinuses, as well as any malignancy.
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            The inverted Schneiderian papilloma: a 25-year study.

            D P Vrabec (1994)
            Inverted papillomas arising from the lateral nasal wall are controversial lesions which have been reported in the medical literature under a variety of titles. The designation "inverted Schneiderian papilloma" is recommended as an appropriate title to best convey the tumor's qualities of inversion, location, and distinctiveness of character. The etiology is uncertain. In the absence of a better explanation of its origin, the tumor should be considered a true epithelial neoplasm. Clinical features in 101 cases seen at the Geisinger Medical Center during the past 25 years are presented. The most frequent presenting complaint was nasal obstruction. The site of origin was the lateral nasal wall in the region of the middle meatus. The most characteristic attributes of the tumor were its tendency to recur, its destructive capacity, and its propensity to be associated with malignancy. To illustrate the pernicious nature of the lesion, a detailed description is given of the extent of bone erosion, the extraordinary sites of tumor extension, and the perioperative complications encountered. A philosophy of management has evolved based on the experiences gained from these 101 patients combined with a review of the experiences of others and study of the regional anatomy. A bold surgical approach is detailed using a lateral rhinotomy incision or a modified Weber-Ferguson incision to expose the tumor adequately and remove it completely. The recurrence rate using this approach was 2%. An associated malignancy was present in 8 patients. Four died of widespread metastases within a year of the diagnosis. The remaining 4 patients are long-term survivors free of disease.
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              Inverted papilloma of the nasal cavity and paranasal sinuses: a Korean multicenter study.

              The study group for sinonasal tumors at the Korean Rhinologic Society analyzed the results of the Korean multicenter experience for sinonasal inverted papilloma (IP) surgeries.
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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                orl
                Revista de otorrinolaringología y cirugía de cabeza y cuello
                Rev. Otorrinolaringol. Cir. Cabeza Cuello
                Sociedad Chilena de Otorrinolaringología, Medicina y Cirugía de Cabeza y Cuello
                0718-4816
                August 2016
                : 76
                : 2
                : 155-159
                Affiliations
                [1 ] Hospital Clínico Regional de Concepción Chile
                [2 ] Hospital Erminda Martín Chile
                Article
                S0718-48162016000200002
                159cd96c-a9d5-42b2-86db-578d8522e9af

                This work is licensed under a Creative Commons Attribution 4.0 International License.

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                SciELO Chile

                Self URI (journal page): http://www.scielo.cl/scielo.php?script=sci_serial&pid=0718-4816&lng=en
                Categories
                OTORHINOLARYNGOLOGY
                SURGERY

                Surgery,Otolaryngology
                Cirugía endoscópica nasal,papiloma invertido nasosinusal,tumor nasosinusal,papiloma schneideriano,Endoscopic sinus surgery,in verted papilloma,sinonasal tumor,Schneiderian papilloma

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