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      On learning what to learn: Heterogeneous observations of dynamics and establishing possibly causal relations among them

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          Abstract

          Before we attempt to (approximately) learn a function between two sets of observables of a physical process, we must first decide what the inputs and outputs of the desired function are going to be. Here we demonstrate two distinct, data-driven ways of first deciding “the right quantities” to relate through such a function, and then proceeding to learn it. This is accomplished by first processing simultaneous heterogeneous data streams (ensembles of time series) from observations of a physical system: records of multiple observation processes of the system. We determine (i) what subsets of observables are common between the observation processes (and therefore observable from each other, relatable through a function); and (ii) what information is unrelated to these common observables, therefore particular to each observation process, and not contributing to the desired function. Any data-driven technique can subsequently be used to learn the input–output relation—from k-nearest neighbors and Geometric Harmonics to Gaussian Processes and Neural Networks. Two particular “twists” of the approach are discussed. The first has to do with the identifiability of particular quantities of interest from the measurements. We now construct mappings from a single set of observations from one process to entire level sets of measurements of the second process, consistent with this single set. The second attempts to relate our framework to a form of causality: if one of the observation processes measures “now,” while the second observation process measures “in the future,” the function to be learned among what is common across observation processes constitutes a dynamical model for the system evolution.

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          Most cited references42

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          Investigating Causal Relations by Econometric Models and Cross-spectral Methods

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            Measuring information transfer

            An information theoretic measure is derived that quantifies the statistical coherence between systems evolving in time. The standard time delayed mutual information fails to distinguish information that is actually exchanged from shared information due to common history and input signals. In our new approach, these influences are excluded by appropriate conditioning of transition probabilities. The resulting transfer entropy is able to distinguish effectively driving and responding elements and to detect asymmetry in the interaction of subsystems.
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              Causality

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                Author and article information

                Contributors
                Role: Editor
                Journal
                PNAS Nexus
                PNAS Nexus
                pnasnexus
                PNAS Nexus
                Oxford University Press (US )
                2752-6542
                December 2024
                06 December 2024
                06 December 2024
                : 3
                : 12
                : pgae494
                Affiliations
                Department of Chemical and Biological Engineering, Princeton University , Princeton, NJ 08544, USA
                School of Computation, Information and Technology, Technical University of Munich , 80333 Munich, Germany
                Faculty of Science, Technology and Medicine, University of Luxembourg , 1350 Kirchberg, Luxembourg
                Viterbi Faculty of Electrical Engineering, Technion, Israel Institute of Technology , Haifa 3200003, Israel
                School of Engineering & Applied Science, Yale University , New Haven, CT 06511, USA
                Electrical & Computer Engineering, Clarkson University , Potsdam, NY 13699, USA
                Department of Chemical and Biomolecular Engineering, Johns Hopkins University , Baltimore, MD 21218, USA
                Department of Applied Mathematics and Statistics, Johns Hopkins University , Baltimore, MD 21218, USA
                Department of Urology, Johns Hopkins University , Baltimore, MD 21218, USA
                Author notes
                To whom correspondence should be addressed: Email: yannisk@ 123456jhu.edu

                Competing Interest: The authors declare no competing interests.

                Author information
                https://orcid.org/0000-0002-2906-1769
                https://orcid.org/0000-0002-5229-4157
                https://orcid.org/0000-0002-6838-1423
                https://orcid.org/0000-0001-7336-7784
                https://orcid.org/0000-0003-2220-3522
                Article
                pgae494
                10.1093/pnasnexus/pgae494
                11630787
                39660076
                15868d60-d514-40f5-ac3c-f515ee957f8c
                © The Author(s) 2024. Published by Oxford University Press on behalf of National Academy of Sciences.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 11 June 2024
                : 27 September 2024
                : 06 December 2024
                Page count
                Pages: 10
                Funding
                Funded by: US DOE;
                Funded by: US AFOSR;
                Funded by: Deutsche Forschungsgemeinschaft, DOI 10.13039/501100001659;
                Funded by: DFG, DOI 10.13039/100004807;
                Funded by: Luxembourg National Research Fund;
                Funded by: FNR, DOI 10.13039/100007869;
                Award ID: 16758846
                Funded by: ONR, DOI 10.13039/100000006;
                Funded by: ARO, DOI 10.13039/100000183;
                Funded by: DARPA RSDN;
                Funded by: NIH, DOI 10.13039/100000002;
                Funded by: NSF, DOI 10.13039/100000001;
                Funded by: CRCNS;
                Categories
                Physical Sciences and Engineering
                AcademicSubjects/MED00010
                AcademicSubjects/SCI00010
                AcademicSubjects/SOC00010
                PNAS_Nexus/app-math
                PNAS_Nexus/math

                heterogeneous observations,learning inputs,common variables,identifiability,causality

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