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Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial
Jesús Villar ,
Carlos Ferrando ,
Domingo Martínez ,
Alfonso Ambrós ,
Tomás Muñoz ,
Juan A Soler ,
Gerardo Aguilar ,
Francisco Alba ,
Elena González-Higueras ,
Luís A Conesa ,
Carmen Martín-Rodríguez ,
Francisco J Díaz-Domínguez ,
Pablo Serna-Grande ,
Rosana Rivas ,
José Ferreres ,
Javier Belda ,
Lucía Capilla ,
Alec Tallet ,
José M Añón ,
Rosa L Fernández ,
Jesús M González-Martín ,
Gerardo Aguilar ,
Francisco Alba ,
Julián Álvarez ,
Alfonso Ambrós ,
José M. Añón ,
María J. Asensio ,
Javier Belda ,
Jesús Blanco ,
Marisa Blasco ,
Lucia Cachafeiro ,
Rafael del Campo ,
Lucía Capilla ,
José A. Carbonell ,
Nieves Carbonell ,
Agustín Cariñena ,
Demetrio Carriedo ,
Mario Chico ,
Luís A. Conesa ,
Ruth Corpas ,
Javier Cuervo ,
Francisco J. Díaz-Domínguez ,
Cristina Domínguez-Antelo ,
Lorena Fernández ,
Rosa L. Fernández ,
Carlos Ferrando ,
José Ferreres ,
Eneritz Gamboa ,
Elena González-Higueras ,
Raúl I. González-Luengo ,
Jesús M. González-Martín ,
Domingo Martínez ,
Carmen Martín-Rodríguez ,
Tomás Muñoz ,
Ramón Ortiz Díaz-Miguel ,
Raquel Pérez-González ,
Ana M. Prieto ,
Isidro Prieto ,
Rosana Rivas ,
Leticia Rojas-Viguera ,
Miguel A. Romera ,
Jesús Sánchez-Ballesteros ,
José M. Segura ,
Pablo Serna-Grande ,
Ainhoa Serrano ,
Rosario Solano ,
Juan A. Soler ,
Marina Soro ,
Alec Tallet ,
Jesús Villar
February 2020
February 2020
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Abstract
<p class="first" id="d4989948e342">There is no proven specific pharmacological treatment
for patients with the acute
respiratory distress syndrome (ARDS). The efficacy of corticosteroids in ARDS remains
controversial. We aimed to assess the effects of dexamethasone in ARDS, which might
change pulmonary and systemic inflammation and result in a decrease in duration of
mechanical ventilation and mortality.
</p>