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      [Tocopherol Succinate Reference Standard (Control 881) of National Institute of Hygienic Sciences].

      Eisei Shikenjo hōkoku. Bulletin of National Institute of Hygienic Sciences
      Chromatography, High Pressure Liquid, Chromatography, Thin Layer, Government Agencies, Hygiene, Japan, Pharmacopoeias as Topic, Tocopherols, Vitamin E, analogs & derivatives, isolation & purification, standards

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          Abstract

          Tocopherol succinate was tested for the preparation of "Tocopherol Succinate Reference Standard (Control 881)". Analytical data obtained were as follows: infrared spectrum, same as Tocopherol Succinate Reference Standard (Control 851); absorbance, E1cm1% (286 nm) = 40.5; thin-layer chromatography, contaminants were not detected until 50 micrograms; high-performance liquid chromatography, three contaminants were detected; loss on drying, 0.09%; assay, 100.0%. On the basis of the above results, this material was authorized as the Japanese Pharmacopoeia Standard (Control 881).

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