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      Using network analysis to identify leverage points based on causal loop diagrams leads to false inference

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          Abstract

          Network analysis is gaining momentum as an accepted practice to identify which factors in causal loop diagrams (CLDs)—mental models that graphically represent causal relationships between a system’s factors—are most likely to shift system-level behaviour, known as leverage points. This application of network analysis, employed to quantitatively identify leverage points without having to use computational modelling approaches that translate CLDs into sets of mathematical equations, has however not been duly reflected upon. We evaluate whether using commonly applied network analysis metrics to identify leverage points is justified, focusing on betweenness- and closeness centrality. First, we assess whether the metrics identify the same leverage points based on CLDs that represent the same system but differ in inferred causal structure—finding that they provide unreliable results. Second, we consider conflicts between assumptions underlying the metrics and CLDs. We recognise six conflicts suggesting that the metrics are not equipped to take key information captured in CLDs into account. In conclusion, using betweenness- and closeness centrality to identify leverage points based on CLDs is at best premature and at worst incorrect—possibly causing erroneous identification of leverage points. This is problematic as, in current practice, the results can inform policy recommendations. Other quantitative or qualitative approaches that better correspond with the system dynamics perspective must be explored.

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          Developing and evaluating complex interventions: the new Medical Research Council guidance

          Evaluating complex interventions is complicated. The Medical Research Council's evaluation framework (2000) brought welcome clarity to the task. Now the council has updated its guidance
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            A new framework for developing and evaluating complex interventions: update of Medical Research Council guidance

            The UK Medical Research Council’s widely used guidance for developing and evaluating complex interventions has been replaced by a new framework, commissioned jointly by the Medical Research Council and the National Institute for Health Research, which takes account of recent developments in theory and methods and the need to maximise the efficiency, use, and impact of research.
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              Centrality in social networks conceptual clarification

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                Author and article information

                Contributors
                l.crielaard@amsterdamumc.nl
                Journal
                Sci Rep
                Sci Rep
                Scientific Reports
                Nature Publishing Group UK (London )
                2045-2322
                29 November 2023
                29 November 2023
                2023
                : 13
                : 21046
                Affiliations
                [1 ]GRID grid.7177.6, ISNI 0000000084992262, Department of Public and Occupational Health, , Amsterdam UMC Location University of Amsterdam, ; Amsterdam, The Netherlands
                [2 ]Institute for Advanced Study, University of Amsterdam, ( https://ror.org/04dkp9463) Amsterdam, The Netherlands
                [3 ]Computational Science Lab, Informatics Institute, University of Amsterdam, ( https://ror.org/04dkp9463) Amsterdam, The Netherlands
                [4 ]GRID grid.5335.0, ISNI 0000000121885934, MRC Epidemiology Unit, Institute of Metabolic Science, , University of Cambridge School of Clinical Medicine, ; Cambridge, UK
                [5 ]POLDER, Institute for Advanced Study, University of Amsterdam, ( https://ror.org/04dkp9463) Amsterdam, The Netherlands
                [6 ]Center for Urban Mental Health, University of Amsterdam, ( https://ror.org/04dkp9463) Amsterdam, The Netherlands
                Article
                46531
                10.1038/s41598-023-46531-z
                10687004
                38030634
                13ef4b63-45d0-4d86-9728-91ad6379f38d
                © The Author(s) 2023

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 1 November 2022
                : 2 November 2023
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100001826, ZonMw;
                Award ID: 531003015
                Categories
                Article
                Custom metadata
                © Springer Nature Limited 2023

                Uncategorized
                public health,complex networks,computational science
                Uncategorized
                public health, complex networks, computational science

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