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Genetic study of 15 STRs loci of Identifiler system in Angola population
Miguel Manuel Melo ,
Mónica Carvalho ,
Virgínia Lopes ,
Maria João Anjos ,
Armando Serra ,
Duarte Nuno Vieira ,
Jorge Sequeiros ,
Francisco Corte-Real
October 2010
October 2010
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Abstract
Angola is located in the African continent, in the area of southern Africa and has
a population of approximately 14 million inhabitants. The Angola population has origin
from Occidental and Southern Bantu people that came from the great lakes region, creating
the most ever known African migration of our days. Allele frequencies for the 15 STRs
loci in the AmpFlSTR Identifiler kit (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, HUMTH01,
D13S317, D16S539, D2S1338, D19S433, HUMVWA, TPOX, D18S51, D5S818, HUMFIBRA/FGA and
including the segment of the X-Y homologous gene amelogenin) were studied for Angola
population. The genotype frequency of the 15 STR loci showed no significant deviations
from Hardy-Weinberg equilibrium expectations and great values for the combined power
of discrimination and combined power of a priori exclusion validate the application
of these markers in forensic genetics. Comparative analyses between Angola population
data and other relevant population database from Africa, Europe and American are presented.