The genotoxicity, metabolism and carcinogenicity of nitrated polycyclic aromatic hydrocarbons – ScienceOpen
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      The genotoxicity, metabolism and carcinogenicity of nitrated polycyclic aromatic hydrocarbons

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      Journal of Environmental Science and Health. Part C: Environmental Carcinogenesis Reviews
      Informa UK Limited

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          Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

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            Atmospheric reactions of polycyclic aromatic hydrocarbons: facile formation of mutagenic nitro derivatives.

            Directly active mutagens are formed on exposure of the promutagen benzo[a]pyrene to gaseous pollutants in smog. In simulated atmospheres containing 1 part per million nitrogen dioxide and traces of nitric acid, directly mutagenic nitro derivatives are readily formed from both benzo[a]pyrene and perylene, a non-mutagen in the Ames reversion assay. Possible formation of direct mutagens by such reactions on sample collection filters, in exhaust effluents, and in the atmosphere should be recognized.
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              Mutagenicity and genotoxicity of nitroarenes

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                Author and article information

                Journal
                Journal of Environmental Science and Health. Part C: Environmental Carcinogenesis Reviews
                Journal of Environmental Science and Health. Part C: Environmental Carcinogenesis Reviews
                Informa UK Limited
                0736-3001
                November 19 2008
                January 1985
                November 19 2008
                January 1985
                : 3
                : 2
                : 221-272
                Article
                10.1080/10590508509373334
                13ba4df5-0e9c-4817-b00a-d3a3c7f43434
                © 1985
                History

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