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      Minimally invasive perinatal and pediatric autopsy with laparoscopically assisted tissue sampling: feasibility and experience of the MinImAL procedure.

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          Abstract

          Less invasive autopsy techniques in cases of fetal or infant death have good acceptability among parents, but the published sampling adequacy in needle biopsy studies is generally poor. Minimally Invasive Autopsy with Laparoscopically assisted sampling (MinImAL) has the potential to increase the diagnostic yield of less invasive autopsy by improving the quality and quantity of tissue samples obtained, whilst permitting visualization, extraction and examination of internal organs through a small incision. The aim of this study was to present the findings of our experience with the MinImAL procedure in cases of fetal, neonatal and pediatric death.

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          Author and article information

          Journal
          Ultrasound Obstet Gynecol
          Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
          Wiley
          1469-0705
          0960-7692
          Nov 2019
          : 54
          : 5
          Affiliations
          [1 ] Department of Histopathology, Great Ormond Street Hospital for Children, London, UK.
          [2 ] UCL Great Ormond Street Institute of Child Health, London, UK.
          [3 ] Department of Paediatric Radiology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
          [4 ] North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
          [5 ] Genetics and Genomic Medicine, UCL Great Ormond Street Institute of Child Health, London, UK.
          Article
          10.1002/uog.20211
          30620444
          13413be8-66c5-4927-8ac3-4a383afe4bc5
          History

          autopsy,histology,minimally invasive autopsy,laparoscopy,perinatal

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