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An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice.
Na-Ri Shin
1 ,
June-Chul Lee ,
Hae-Youn Lee ,
Min-Soo Kim ,
Tae Woong Whon ,
Myung-Shik Lee ,
Jin-Woo Bae
May 2014
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Abstract
Recent evidence indicates that the composition of the gut microbiota contributes to the development of metabolic disorders by affecting the physiology and metabolism of the host. Metformin is one of the most widely prescribed type 2 diabetes (T2D) therapeutic agents.