Influence of histamine on the expression of CCL20 in human gingival fibroblasts.

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Abstract

Histamine plays an important role during allergic and inflammatory reactions, and it has been suggested to influence periodontal inflammation. The aim of this study was to investigate the effects of histamine on the expression of the antimicrobial peptide C-C chemokine ligand 20 (CCL20) in human gingival fibroblasts (HGFs) when exposed to toll-like receptor (TLR) agonists.

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Journal

Journal ID (iso-abbrev): J. Periodont. Res.

Title: Journal of periodontal research

Publisher: Wiley-Blackwell

ISSN (Electronic): 1600-0765

ISSN (Print): 0022-3484

Publication date (Electronic): Dec 2015

Volume: 50

Issue: 6

Affiliations

[1 ] Department of Periodontology and Synoptic Dentistry, Charité - University Medicine Berlin, Berlin, Germany.

[2 ] Department of Oral Health Sciences, Health Science Center, University of Washington, Seattle, WA, USA.

[3 ] Department of Periodontology, Operative and Preventive Dentistry, University Hospital Bonn, Bonn, Germany.

Article

DOI: 10.1111/jre.12265

PubMed ID: 25712856

SO-VID: 13099a66-3b86-4448-a0d4-e0f747a3f5bf

History

Keywords: C-C-chemokine ligand 20,antimicrobial peptides,histamine,histamine-1-receptor,human gingival fibroblast,innate immunity,interleukin-8

Data availability:

Keywords: C-C-chemokine ligand 20, antimicrobial peptides, histamine, histamine-1-receptor, human gingival fibroblast, innate immunity, interleukin-8

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