Effect of glycosides based standardized fenugreek seed extract in bleomycin-induced pulmonary fibrosis in rats: Decisive role of Bax, Nrf2, NF-κB, Muc5ac, TNF-α and IL-1β.

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Abstract

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive multifactorial disease with limited therapeutic options. Glycosides based standardized fenugreek seed extract (SFSE-G) possesses potent anti-inflammatory and anti-oxidant property.

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Journal ID (iso-abbrev): Chem. Biol. Interact.

Title: Chemico-biological interactions

ISSN (Electronic): 1872-7786

ISSN (Print): 0009-2797

Publication date (Electronic): Jul 25 2015

Volume: 237

Affiliations

[1 ] Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Erandwane, Paud Road, Pune 411 038, India.

[2 ] Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Erandwane, Paud Road, Pune 411 038, India. Electronic address: sbodhindus@gmail.com.

[3 ] Indus Biotech Private Limited, 1, Rahul Residency, Off Salunke Vihar Road, Kondhwa, Pune 411 048, India.

Article

Publisher Item ID: S0009-2797(15)00250-1

DOI: 10.1016/j.cbi.2015.06.019

PubMed ID: 26093215

SO-VID: 12f2b22e-6f63-4848-95e2-45cb14266f60

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Keywords: Bleomycin,Muc5ac,NF-κB,Nrf2,Pulmonary fibrosis,Standardized fenugreek seeds extract

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Keywords: Bleomycin, Muc5ac, NF-κB, Nrf2, Pulmonary fibrosis, Standardized fenugreek seeds extract

Effect of glycosides based standardized fenugreek seed extract in bleomycin-induced pulmonary fibrosis in rats: Decisive role of Bax, Nrf2, NF-κB, Muc5ac, TNF-α and IL-1β.

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