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      Depression, anxiety and stress after COVID-19 vaccination: A retrospective cross-sectional study among health care providers

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          Abstract

          Background:

          Corona virus disease (COVID-19) is a health concern that produced considerable psychological and physical health challenges to Health care providers (HCPs) internationally.

          Aims:

          This study aims to determine the level of depression, anxiety, and stress after receiving the COVID-19 vaccine among HCPs in Iraq.

          Methods:

          A retrospective cross-sectional study design was used in this study. The participants involved were 700 Iraqi HCPs who received one or two doses from COVID-19 vaccines. The questionnaire was designed and brought to them electronically using Google form and distributed by social media. Then mental health status was measured using a specific depression, anxiety and stress scale named DASS-21. Each domain of the DASS scale was calculated for each subject and DASS-21 scores were compared between different demographic groups.

          Results:

          Females represented a large percentage of participants (80%). The majority of participants had a normal level of DASS-21 after receiving the vaccine. Higher scores were obtained among graduated young age groups also among individuals who have side effects associated with the vaccine.

          Conclusions:

          To the best of our knowledge, this is the first study that assesses mental health after receiving the COVID-19 vaccine in the middle east. The study concluded that HCPs have low DASS-21 scores and this gives us promising results for the use of the COVID-19 vaccine in future.

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          Most cited references30

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          Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China

          Background: The 2019 coronavirus disease (COVID-19) epidemic is a public health emergency of international concern and poses a challenge to psychological resilience. Research data are needed to develop evidence-driven strategies to reduce adverse psychological impacts and psychiatric symptoms during the epidemic. The aim of this study was to survey the general public in China to better understand their levels of psychological impact, anxiety, depression, and stress during the initial stage of the COVID-19 outbreak. The data will be used for future reference. Methods: From 31 January to 2 February 2020, we conducted an online survey using snowball sampling techniques. The online survey collected information on demographic data, physical symptoms in the past 14 days, contact history with COVID-19, knowledge and concerns about COVID-19, precautionary measures against COVID-19, and additional information required with respect to COVID-19. Psychological impact was assessed by the Impact of Event Scale-Revised (IES-R), and mental health status was assessed by the Depression, Anxiety and Stress Scale (DASS-21). Results: This study included 1210 respondents from 194 cities in China. In total, 53.8% of respondents rated the psychological impact of the outbreak as moderate or severe; 16.5% reported moderate to severe depressive symptoms; 28.8% reported moderate to severe anxiety symptoms; and 8.1% reported moderate to severe stress levels. Most respondents spent 20–24 h per day at home (84.7%); were worried about their family members contracting COVID-19 (75.2%); and were satisfied with the amount of health information available (75.1%). Female gender, student status, specific physical symptoms (e.g., myalgia, dizziness, coryza), and poor self-rated health status were significantly associated with a greater psychological impact of the outbreak and higher levels of stress, anxiety, and depression (p < 0.05). Specific up-to-date and accurate health information (e.g., treatment, local outbreak situation) and particular precautionary measures (e.g., hand hygiene, wearing a mask) were associated with a lower psychological impact of the outbreak and lower levels of stress, anxiety, and depression (p < 0.05). Conclusions: During the initial phase of the COVID-19 outbreak in China, more than half of the respondents rated the psychological impact as moderate-to-severe, and about one-third reported moderate-to-severe anxiety. Our findings identify factors associated with a lower level of psychological impact and better mental health status that can be used to formulate psychological interventions to improve the mental health of vulnerable groups during the COVID-19 epidemic.
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            The structure of negative emotional states: Comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories

            The psychometric properties of the Depression Anxiety Stress Scales (DASS) were evaluated in a normal sample of N = 717 who were also administered the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI). The DASS was shown to possess satisfactory psychometric properties, and the factor structure was substantiated both by exploratory and confirmatory factor analysis. In comparison to the BDI and BAI, the DASS scales showed greater separation in factor loadings. The DASS Anxiety scale correlated 0.81 with the BAI, and the DASS Depression scale correlated 0.74 with the BDI. Factor analyses suggested that the BDI differs from the DASS Depression scale primarily in that the BDI includes items such as weight loss, insomnia, somatic preoccupation and irritability, which fail to discriminate between depression and other affective states. The factor structure of the combined BDI and BAI items was virtually identical to that reported by Beck for a sample of diagnosed depressed and anxious patients, supporting the view that these clinical states are more severe expressions of the same states that may be discerned in normals. Implications of the results for the conceptualisation of depression, anxiety and tension/stress are considered, and the utility of the DASS scales in discriminating between these constructs is discussed.
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              Impact of the COVID-19 Pandemic on Mental Health and Quality of Life among Local Residents in Liaoning Province, China: A Cross-Sectional Study

              Our study aimed to investigate the immediate impact of the COVID-19 pandemic on mental health and quality of life among local Chinese residents aged ≥18 years in Liaoning Province, mainland China. An online survey was distributed through a social media platform between January and February 2020. Participants completed a modified validated questionnaire that assessed the Impact of Event Scale (IES), indicators of negative mental health impacts, social and family support, and mental health-related lifestyle changes. A total of 263 participants (106 males and 157 females) completed the study. The mean age of the participants was 37.7 ± 14.0 years, and 74.9% had a high level of education. The mean IES score in the participants was 13.6 ± 7.7, reflecting a mild stressful impact. Only 7.6% of participants had an IES score ≥26. The majority of participants (53.3%) did not feel helpless due to the pandemic. On the other hand, 52.1% of participants felt horrified and apprehensive due to the pandemic. Additionally, the majority of participants (57.8–77.9%) received increased support from friends and family members, increased shared feeling and caring with family members and others. In conclusion, the COVID-19 pandemic was associated with mild stressful impact in our sample, even though the COVID-19 pandemic is still ongoing. These findings would need to be verified in larger population studies.
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                Author and article information

                Contributors
                Journal
                Pharm Pract (Granada)
                Pharm Pract (Granada)
                Pharmacy Practice
                Centro de Investigaciones y Publicaciones Farmaceuticas
                1885-642X
                1886-3655
                Jul-Sep 2022
                12 July 2022
                : 20
                : 3
                : 2689
                Affiliations
                MSc. Department of Clinical Pharmacy, College of Pharmacy, University of Mosul , Ninevah 81011, Iraq. l.m.saadallah@ 123456uomosul.edu.iq
                MSc. Department of Clinical Pharmacy, College of Pharmacy, University of Mosul , Ninevah 81011, Iraq. heba.attash@ 123456uomosul.edu.iq
                PhD. Department of Clinical Pharmacy, College of Pharmacy, University of Mosul , Ninevah 81011, Iraq. al_qazaz73@ 123456uomosul.edu.iq
                Author information
                https://orcid.org/0000-0002-7794-1373
                https://orcid.org/0000-0002-0676-1156
                https://orcid.org/0000-0002-5223-0065
                Article
                pharmpract-20-2689
                10.18549/PharmPract.2022.3.2689
                9851821
                36733523
                12dceb93-f650-4dbf-9677-d66cb2bb0712
                Copyright: © Pharmacy Practice

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY-NC-ND 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 31 May 2022
                : 08 June 2022
                Categories
                Original Research

                covid-19,vaccine,stress,anxiety,depression,health care providers

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