Augmenting nerve regeneration with electrical stimulation.

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Abstract

Poor functional recovery after peripheral nerve injury is generally attributed to irreversible target atrophy. In rats, we addressed the functional outcomes of prolonged neuronal separation from targets (chronic axotomy for up to 1 year) and atrophy of Schwann cells (SCs) in distal nerve stumps, and whether electrical stimulation (ES) accelerates axon regeneration. In carpal tunnel syndrome (CTS) patients with severe axon degeneration and release surgery, we asked whether ES accelerates muscle reinnervation.

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Journal

Journal ID (iso-abbrev): Neurol Res

Title: Neurological research

Publisher: Maney Publishing

ISSN: 0161-6412

ISSN (Print): 0161-6412

Publication date (Electronic): Dec 2008

Volume: 30

Issue: 10

Affiliations

[1 ] Division of Physical Medicine and Rehabilitation/Centre for Neuroscience, Faculty of Medicine, University of Alberta, Edmonton, Alta T6G 2S2, Canada.

Article

DOI: 10.1179/174313208X362488

PubMed ID: 19079975

SO-VID: 12599506-b25d-4e0b-b6a5-57b161138751

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