Extracellular vesicles in immunomodulation and tumor progression

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Abstract

Extracellular vesicles have emerged as prominent regulators of the immune response during tumor progression. EVs contain a diverse repertoire of molecular cargo that plays a critical role in immunomodulation. Here, we identify the role of EVs as mediators of communication between cancer and immune cells. This expanded role of EVs may shed light on the mechanisms behind tumor progression and provide translational diagnostic and prognostic tools for immunologists.

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Contributors

Bartholomew Starich: (View ORCID Profile)

Denis Wirtz: (View ORCID Profile)

Journal

Title: Nature Immunology

Abbreviated Title: Nat Immunol

Publisher: Springer Science and Business Media LLC

ISSN (Print): 1529-2908

ISSN (Electronic): 1529-2916

Publication date (Electronic): March 22 2021

Article

DOI: 10.1038/s41590-021-00899-0

PMC ID: 9389600

PubMed ID: 33753940

SO-VID: 120c08b4-840f-4b56-ad99-cfdec67cca04

License:

http://www.springer.com/tdm

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