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      Cell-free plasma DNA as a predictor of outcome in severe sepsis and septic shock.

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          Abstract

          Increased concentrations of cell-free DNA have been found in plasma of septic and critically ill patients. We investigated the value of plasma DNA for the prediction of intensive care unit (ICU) and hospital mortality and its association with the degree of organ dysfunction and disease severity in patients with severe sepsis.

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          Author and article information

          Journal
          Clin Chem
          Clinical chemistry
          American Association for Clinical Chemistry (AACC)
          0009-9147
          0009-9147
          Jun 2008
          : 54
          : 6
          Affiliations
          [1 ] Departments of Medicine and Emergency Care, Helsinki University Central Hospital, Helsinki, Finland. katri.saukkonen@helsinki.fi
          Article
          clinchem.2007.101030
          10.1373/clinchem.2007.101030
          18420731
          110868e6-1c21-4557-bc5a-03fd0cccac0b
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