Dapagliflozin Plus Saxagliptin Add-on Therapy Compared With Insulin in Patients With Type 2 Diabetes Poorly Controlled by Metformin With or Without Sulfonylurea Therapy: A Randomized Clinical Trial.

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Abstract

This study evaluated whether an oral combination of a sodium-glucose cotransporter 2 inhibitor and a dipeptidyl peptidase 4 inhibitor achieved glycemic control similar to basal insulin in patients with type 2 diabetes, poorly controlled with metformin, without increasing hypoglycemia or body weight.

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Journal

Journal ID (iso-abbrev): Diabetes Care

Title: Diabetes care

Publisher: American Diabetes Association

ISSN (Electronic): 1935-5548

ISSN (Print): 0149-5992

Publication date (Electronic): August 2019

Volume: 42

Issue: 8

Affiliations

[1 ] Steno Diabetes Center Copenhagen, University of Copenhagen, Copenhagen, Denmark t.vilsboll@dadlnet.dk.

[2 ] AstraZeneca Gothenburg, Mölndal, Sweden.

[3 ] AstraZeneca, Gaithersburg, MD.

[4 ] Division of Endocrinology, Thomas Jefferson University Hospital, Philadelphia, PA.

[5 ] Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.

Article

Publisher Item ID: dc18-1988

DOI: 10.2337/dc18-1988

PubMed ID: 31167892

SO-VID: 109946ba-24a1-48e2-a5b8-b8248a24266d

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