Factors Affecting Image Quality and Lesion Evaluability in Breast Diffusion-weighted MRI: Observations from the ECOG-ACRIN Cancer Research Group Multisite Trial (A6702).

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Abstract

The A6702 multisite trial confirmed that apparent diffusion coefficient (ADC) measures can improve breast MRI accuracy and reduce unnecessary biopsies, but also found that technical issues rendered many lesions non-evaluable on diffusion-weighted imaging (DWI). This secondary analysis investigated factors affecting lesion evaluability and impact on diagnostic performance.

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Journal

Journal ID (iso-abbrev): J Breast Imaging

Title: Journal of breast imaging

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 2631-6129

ISSN (Print): 2631-6110

Publication date (Electronic): February 6 2021

Volume: 3

Issue: 1

Affiliations

[1 ] Vanderbilt University Medical Center, Department of Medicine, Nashville, TN.

[2 ] Vanderbilt-Ingram Cancer Center, Nashville, TN.

[3 ] Brown University, Center for Statistical Sciences, Providence, RI.

[4 ] University of Washington, Department of Radiology, Seattle, WA.

[5 ] Vanderbilt University Medical Center, Department of Radiology and Radiological Sciences, Nashville, TN.

[6 ] New York University School of Medicine, Department of Radiology, New York, NY.

[7 ] Stanford University School of Medicine, Department of Radiology, Stanford, CA.

[8 ] University of Texas Southwestern Medical Center, Department of Diagnostic Radiology, Dallas, TX.

[9 ] MD Anderson Cancer Center, Department of Breast Imaging, Houston, TX.

[10 ] Northwestern University Feinberg School of Medicine, Department of Radiology, Chicago, IL.

[11 ] University of California San Francisco School of Medicine, Department of Radiology and Biomedical Engineering, San Francisco, CA.

[12 ] Oregon Health and Science University, Department of Radiology, Portland, OR.

[13 ] University of Michigan, Department of Radiology/MRI, Ann Arbor, MI.

[14 ] University of Pennsylvania Perelman School of Medicine, Department of Radiology, Philadelphia, PA.

[15 ] Memorial Sloan-Kettering Cancer Center, Department of Radiology, New York, NY.

[16 ] University of Texas Austin, Department of Biomedical Engineering, Austin, TX.

Article

Publisher Item ID: wbaa103

DOI: 10.1093/jbi/wbaa103

PMC ID: 7835633

PubMed ID: 33543122

SO-VID: 0fcdea22-0468-4390-82f6-7c1a2d663abb

History

Keywords: apparent diffusion coefficient (ADC),artifacts,breast magnetic resonance imaging (MRI),diagnostic performance,multicenter trial

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Keywords: apparent diffusion coefficient (ADC), artifacts, breast magnetic resonance imaging (MRI), diagnostic performance, multicenter trial

Factors Affecting Image Quality and Lesion Evaluability in Breast Diffusion-weighted MRI: Observations from the ECOG-ACRIN Cancer Research Group Multisite Trial (A6702).

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