Sex-specific effects of psychedelics on prepulse inhibition of startle in 129S6/SvEv mice.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Prepulse inhibition (PPI) of startle is a sensorimotor gating phenomenon perturbed in a variety of neuropsychiatric conditions. Psychedelics disrupt PPI in rats and humans, but their effects and involvement of the serotonin 5-HT2A receptor (5-HT2AR) in mice remain unexplored.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Psychopharmacology (Berl)

Title: Psychopharmacology

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1432-2072

ISSN (Print): 0033-3158

Publication date (Electronic): Jun 2022

Volume: 239

Issue: 6

Affiliations

[1 ] Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA.

[2 ] Department of Pharmacology and Toxicology, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA.

[3 ] Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, 23298, USA.

[4 ] Medical Psychology Unit, Department of Psychiatry and Forensic Medicine, Institute of Neurosciences, School of Medicine, Universidad Autónoma de Barcelona, E-08193, Bellaterra, Barcelona, Spain.

[5 ] VCU Alcohol Research Center, Virginia Commonwealth University, Richmond, VA, 23298, USA.

[6 ] Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond, VA, 23298, USA.

[7 ] Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA. javier.maeso@vcuhealth.org.

Article

Publisher Item ID: 10.1007/s00213-021-05913-9

DOI: 10.1007/s00213-021-05913-9

PubMed ID: 34345931

SO-VID: 0f5f7f5c-96ca-456c-bfe4-e7a7f9b3a35e

History

Keywords: Hallucinogens,Sex differences,Serotonin 5-HT2A receptor,Sensorimotor gating,Psychopharmacology,Psychedelics,Psilocybin,Prepulse inhibition (PPI),Lysergic acid diethylamide (LSD),G protein-coupled receptor (GPCR)

Data availability:

Keywords: Hallucinogens, Sex differences, Serotonin 5-HT2A receptor, Sensorimotor gating, Psychopharmacology, Psychedelics, Psilocybin, Prepulse inhibition (PPI), Lysergic acid diethylamide (LSD), G protein-coupled receptor (GPCR)

Comments

Comment on this article

scite_

Smart Citations

Citing PublicationsSupportingMentioningContrasting

View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

Cited by 6

See all cited by