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      Wealth and inequality gradients for the detection and control of hypertension in older individuals in middle-income economies around 2007-2015

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          Abstract

          Socioeconomic inequalities in the detection and treatment of non-communicable diseases represent a challenge for healthcare systems in middle-income countries (MICs) in the context of population ageing. This challenge is particularly pressing regarding hypertension due to its increasing prevalence among older individuals in MICs, especially among those with lower socioeconomic status (SES). Using comparative data for China, Colombia, Ghana, India, Mexico, Russia and South Africa, we systematically assess the association between SES, measured in the form of a wealth index, and hypertension detection and control around the years 2007-15. Furthermore, we determine what observable factors, such as socio-demographic and health characteristics, explain existing SES-related inequalities in hypertension detection and control using a Blinder-Oaxaca decomposition. Results show that the prevalence of undetected hypertension is significantly associated with lower SES. For uncontrolled hypertension, there is evidence of a significant gradient in three of the six countries at the time the data were collected. Differences between rural and urban areas as well as lower and higher educated individuals account for the largest proportion of SES-inequalities in hypertension detection and control at the time. Improved access to primary healthcare in MICs since then may have contributed to a reduction in health inequalities in detection and treatment of hypertension. However, whether this indeed has been the case remains to be investigated.

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          Prevalence, awareness, treatment, and control of hypertension in rural and urban communities in high-, middle-, and low-income countries.

          Hypertension is the most important preventable cause of morbidity and mortality globally, yet there are relatively few data collected using standardized methods. To examine hypertension prevalence, awareness, treatment, and control in participants at baseline in the Prospective Urban Rural Epidemiology (PURE) study. A cross-sectional study of 153,996 adults (complete data for this analysis on 142,042) aged 35 to 70 years, recruited between January 2003 and December 2009. Participants were from 628 communities in 3 high-income countries (HIC), 10 upper-middle-income and low-middle-income countries (UMIC and LMIC), and 4 low-income countries (LIC). Hypertension was defined as individuals with self-reported treated hypertension or with an average of 2 blood pressure measurements of at least 140/90 mm Hg using an automated digital device. Awareness was based on self-reports, treatment was based on the regular use of blood pressure-lowering medications, and control was defined as individuals with blood pressure lower than 140/90 mm Hg. Among the 142,042 participants, 57,840 (40.8%; 95% CI, 40.5%-41.0%) had hypertension and 26,877 (46.5%; 95% CI, 46.1%-46.9%) were aware of the diagnosis. Of those who were aware of the diagnosis, the majority (23,510 [87.5%; 95% CI, 87.1%-87.9%] of those who were aware) were receiving pharmacological treatments, but only a minority of those receiving treatment were controlled (7634 [32.5%; 95% CI, 31.9%-33.1%]). Overall, 30.8%, 95% CI, 30.2%-31.4% of treated patients were taking 2 or more types of blood pressure-lowering medications. The percentages aware (49.0% [95% CI, 47.8%-50.3%] in HICs, 52.5% [95% CI, 51.8%-53.2%] in UMICs, 43.6% [95% CI, 42.9%-44.2%] in LMICs, and 40.8% [95% CI, 39.9%-41.8%] in LICs) and treated (46.7% [95% CI, 45.5%-47.9%] in HICs, 48.3%, [95% CI, 47.6%-49.1%] in UMICs, 36.9%, [95% CI, 36.3%-37.6%] in LMICs, and 31.7% [95% CI, 30.8%-32.6%] in LICs) were lower in LICs compared with all other countries for awareness (P <.001) and treatment (P <.001). Awareness, treatment, and control of hypertension were higher in urban communities compared with rural ones in LICs (urban vs rural, P <.001) and LMICs (urban vs rural, P <.001), but similar for other countries. Low education was associated with lower rates of awareness, treatment, and control in LICs, but not in other countries. Among a multinational study population, 46.5% of participants with hypertension were aware of the diagnosis, with blood pressure control among 32.5% of those being treated. These findings suggest substantial room for improvement in hypertension diagnosis and treatment.
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            The Blinder–Oaxaca Decomposition for Linear Regression Models

            Ben Jann (2018)
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              Prevention and management of chronic disease: a litmus test for health-systems strengthening in low-income and middle-income countries.

              National health systems need strengthening if they are to meet the growing challenge of chronic diseases in low-income and middle-income countries. By application of an accepted health-systems framework to the evidence, we report that the factors that limit countries' capacity to implement proven strategies for chronic diseases relate to the way in which health systems are designed and function. Substantial constraints are apparent across each of the six key health-systems components of health financing, governance, health workforce, health information, medical products and technologies, and health-service delivery. These constraints have become more evident as development partners have accelerated efforts to respond to HIV, tuberculosis, malaria, and vaccine-preventable diseases. A new global agenda for health-systems strengthening is arising from the urgent need to scale up and sustain these priority interventions. Most chronic diseases are neglected in this dialogue about health systems, despite the fact that non-communicable diseases (most of which are chronic) will account for 69% of all global deaths by 2030 with 80% of these deaths in low-income and middle-income countries. At the same time, advocates for action against chronic diseases are not paying enough attention to health systems as part of an effective response. Efforts to scale up interventions for management of common chronic diseases in these countries tend to focus on one disease and its causes, and are often fragmented and vertical. Evidence is emerging that chronic disease interventions could contribute to strengthening the capacity of health systems to deliver a comprehensive range of services-provided that such investments are planned to include these broad objectives. Because effective chronic disease programmes are highly dependent on well-functioning national health systems, chronic diseases should be a litmus test for health-systems strengthening. Copyright © 2010 Elsevier Ltd. All rights reserved.
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                Author and article information

                Contributors
                Role: Data curationRole: Formal analysisRole: SoftwareRole: Visualization
                Role: ConceptualizationRole: MethodologyRole: ValidationRole: Writing – original draftRole: Writing – review & editing
                Role: ConceptualizationRole: Data curationRole: Funding acquisitionRole: MethodologyRole: Project administrationRole: SoftwareRole: VisualizationRole: Writing – original draftRole: Writing – review & editing
                Role: Editor
                Journal
                PLoS One
                PLoS One
                plos
                PLoS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                2022
                8 July 2022
                : 17
                : 7
                : e0269118
                Affiliations
                [1 ] School of Economics, Universidad del Rosario, Bogotá, Colombia
                [2 ] Escuela de Gobierno, Universidad de los Andes, Bogotá, Colombia
                [3 ] Swiss Tropical and Public Health Institute, Basel, Switzerland
                SRM Institute of Science and Technology, INDIA
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                Author information
                https://orcid.org/0000-0002-8754-5710
                https://orcid.org/0000-0003-1058-3062
                Article
                PONE-D-21-31685
                10.1371/journal.pone.0269118
                9269405
                35802577
                0ef66469-dc92-4fcd-9729-d19ee88a1cee
                © 2022 García et al

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 1 October 2021
                : 15 May 2022
                Page count
                Figures: 4, Tables: 2, Pages: 17
                Funding
                Funded by: IDRC
                Award ID: GADC project grant number 108442-001
                Award Recipient :
                Funded by: World Bank Group and Colombian Ministry of Science, Technology and Innovation (MINCIENCIAS)
                Award ID: Fulbright-Colciencias and Colombia Cientifica – Alianza EFI 60185 contract FP44842- 220-2018
                Award Recipient :
                GADC project by the CIHR/IDRC [grant number 108442-001] Fulbright-Colciencias and Colombia Cientifica – Alianza EFI 60185 contract FP44842- 220-2018, funded by The World Bank through the Scientific Ecosystems, managed by the Colombian Ministry of Science, Technology and Innovation (MINCIENCIAS). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
                Categories
                Research Article
                Medicine and Health Sciences
                Health Care
                Socioeconomic Aspects of Health
                Medicine and Health Sciences
                Public and Occupational Health
                Socioeconomic Aspects of Health
                Social Sciences
                Economics
                Health Economics
                Health Insurance
                Medicine and Health Sciences
                Health Care
                Health Economics
                Health Insurance
                People and places
                Geographical locations
                South America
                Colombia
                People and Places
                Geographical Locations
                Asia
                Russia
                People and Places
                Geographical Locations
                Europe
                Russia
                People and Places
                Geographical Locations
                Africa
                Ghana
                People and Places
                Geographical Locations
                Asia
                India
                Medicine and Health Sciences
                Vascular Medicine
                Blood Pressure
                Hypertension
                People and places
                Geographical locations
                North America
                Mexico
                Custom metadata
                Minimum replication scripts and data is avaialable at: https://github.com/androdri1/HBP_wealthgradient Full data is available at the SAGE project webpage: https://apps.who.int/healthinfo/systems/surveydata/index.php/catalog/sage/about And upon request to Ministerio de Salud y Protección Social de Colombia: Dirección de Epidemiología y Demografía, which should be done through the webpage: https://tramites.minsalud.gov.co/tramitesservicios/.

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