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      Study protocol: Project 2VIDA! SARS-CoV-2 vaccine intervention delivery for adults in Southern California

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          Abstract

          Background

          To date, the United States (US) leads the world in the number of infections and deaths due to the Coronavirus Disease 2019 (COVID-19). Racial and ethnic disparities in COVID-19 morbidity and mortality are staggering. Age-adjusted data show that AA and Latino individuals have had higher rates of death over most of the pandemic and during surges. Project 2VIDA! is community-based participatory research (CBPR) that was developed to address individual, social, and contextual factors related to access and acceptance of the COVID-19 vaccine among African American and Latino communities in Southern California. This paper describes the study protocol and overarching objectives.

          Methods and design

          Project 2VIDA! is a multilevel intervention that builds on the principals of CBPR and is designed to increase uptake of the COVID-19 vaccine among African American and Latino individuals (≥16 years and older) in San Diego County. The intervention was developed with a working group comprised of representatives from community and academia and centers on targeted COVID-19 individual awareness and education, linkage to medical and supportive services, COVID-19 community outreach and health promotion and offering the COVID-19 vaccine through community pop-up clinics.

          Discussion

          Findings from 2VIDA! will provide data on the impact, feasibility, and acceptability of the intervention which are all crucial for the adaptation, refinement, and improvement of vaccine outreach interventions for COVID-19 and other vaccine preventable infectious diseases that severely impact African American and Latino communities.

          Clinical trial registration

          https://clinicaltrials.gov/ct2/show/NCT05022472?term=Project+2VIDA&draw=2&rank=1, NCT05022472.

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          Most cited references33

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          Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

          Safiya Richardson, Jamie Hirsch, Mangala Narasimhan … (2020)
          There is limited information describing the presenting characteristics and outcomes of US patients requiring hospitalization for coronavirus disease 2019 (COVID-19).
          Article 0 comments Cited 4755 times – based on 0 reviews     Review now
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            Vaccine hesitancy: Definition, scope and determinants.

            Noni MacDonald (2015)
            The SAGE Working Group on Vaccine Hesitancy concluded that vaccine hesitancy refers to delay in acceptance or refusal of vaccination despite availability of vaccination services. Vaccine hesitancy is complex and context specific, varying across time, place and vaccines. It is influenced by factors such as complacency, convenience and confidence. The Working Group retained the term 'vaccine' rather than 'vaccination' hesitancy, although the latter more correctly implies the broader range of immunization concerns, as vaccine hesitancy is the more commonly used term. While high levels of hesitancy lead to low vaccine demand, low levels of hesitancy do not necessarily mean high vaccine demand. The Vaccine Hesitancy Determinants Matrix displays the factors influencing the behavioral decision to accept, delay or reject some or all vaccines under three categories: contextual, individual and group, and vaccine/vaccination-specific influences.
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              COVID-19 and Racial/Ethnic Disparities

              Monica Webb Hooper, Anna Maria Nápoles, Eliseo J. Pérez-Stable (2020)
              Article 0 comments Cited 1069 times – based on 0 reviews     Review now
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                Author and article information

                Contributors
                Britt Skaathun: Role: Role: Role: Role: Role:
                Linda Salgin: Role: Role: Role:
                Fatima A. Muñoz: Role: Role: Role: Role: Role: Role: Role: Role: Role: Role: Role:
                Gregory A. Talavera: URI : https://loop.frontiersin.org/people/1521145/overviewRole: Role: Role:
                Davey M. Smith: Role: Role: Role: Role: Role: Role:
                Jamila K. Stockman: Role: Role: Role:
                Sophie E. O’Bryan: URI : https://loop.frontiersin.org/people/2669504/overviewRole: Role: Role: Role:
                Daniel Ramirez: Role: Role: Role: Role:
                Cynthia James-Price: Role: Role: Role: Role:
                Argentina E. Servin: URI : https://loop.frontiersin.org/people/2426660/overviewRole: Role: Role: Role: Role: Role: Role: Role: Role: Role: Role: Role: Role: Role:
                Journal
                Journal ID (nlm-ta): Front Public Health
                Journal ID (iso-abbrev): Front Public Health
                Journal ID (publisher-id): Front. Public Health
                Title: Frontiers in Public Health
                Publisher: Frontiers Media S.A.
                ISSN (Electronic): 2296-2565
                Publication date (Electronic): 14 March 2024
                Publication date Collection: 2024
                Volume: 12
                Electronic Location Identifier: 1291332
                Affiliations
                [1] 1School of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego , La Jolla, CA, United States
                [2] 2San Ysidro Health Center , San Diego, CA, United States
                [3] 3Multicultural Health Foundation , San Diego, CA, United States
                Author notes

                Edited by: Mark Servis, University of California, Davis, United States

                Reviewed by: Chung-Chien Huang, Taipei Medical University, Taiwan

                B. Shayak, University of Maryland, United States

                Dickson Adom, Kwame Nkrumah University of Science and Technology, Ghana

                *Correspondence: Argentina E. Servin, arservin@ 123456ucsd.edu
                Article
                DOI: 10.3389/fpubh.2024.1291332
                PMC ID: 10977100
                PubMed ID: 38550328
                SO-VID: 0e8fa674-d032-4ec3-86ba-c35dfdc667e4
                Copyright © Copyright © 2024 Skaathun, Salgin, Muñoz, Talavera, Smith, Stockman, O’Bryan, Ramirez, James-Price and Servin.
                License:

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                Date received : 09 September 2023
                Date accepted : 28 February 2024
                Page count
                Figures: 3, Tables: 0, Equations: 0, References: 49, Pages: 10, Words: 7526
                Funding
                The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This work was supported by the National Institutes of Health (NIH)/National Institute on Minority Health and Health Disparities (NIMHD) Grant Number: R01MD016872 (PI: AS).
                Categories
                Subject: Public Health
                Subject: Study Protocol
                Custom metadata
                section-at-acceptance Public Health Education and Promotion

                Keywords: covid-19,african american,latino (hispanic),vaccine hesitancy,community-based participatory research
                Data availability:
                Keywords: covid-19, african american, latino (hispanic), vaccine hesitancy, community-based participatory research

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