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      Obesity wars: molecular progress confronts an expanding epidemic.

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      Cell
      Elsevier BV

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          Abstract

          The worldwide prevalence of obesity is increasing at an alarming rate, with major adverse consequences for human health. This "obesity epidemic" is paralleled by a rapid and substantive increase in our understanding of molecular pathways and physiologic systems underlying the regulation of energy balance. While efforts to address the environmental factors that are responsible for the recent "epidemic" must continue, new molecular and physiologic insights into this system offer exciting possibilities for future development of successful therapies.

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          Author and article information

          Journal
          Cell
          Cell
          Elsevier BV
          0092-8674
          0092-8674
          Jan 23 2004
          : 116
          : 2
          Affiliations
          [1 ] Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. jflier@bidmc.harvard.edu
          Article
          S009286740301081X
          10.1016/s0092-8674(03)01081-x
          14744442
          0b9c94e1-b405-4df9-b0cd-1f29c36f26ae
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