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      High flow nasal cannulae oxygen therapy in acute-moderate hypercapnic respiratory failure

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          Abstract

          <p class="first" id="d1588442e123">Severe acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a significant event that results in substantial mortality. </p>

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          High-Flow Nasal Oxygen vs Noninvasive Positive Airway Pressure in Hypoxemic Patients After Cardiothoracic Surgery: A Randomized Clinical Trial.

          François Stephan, Benoit Barrucand, Pascal Petit … (2015)
          Noninvasive ventilation delivered as bilevel positive airway pressure (BiPAP) is often used to avoid reintubation and improve outcomes of patients with hypoxemia after cardiothoracic surgery. High-flow nasal oxygen therapy is increasingly used to improve oxygenation because of its ease of implementation, tolerance, and clinical effectiveness.
          Article 0 comments Cited 150 times – based on 0 reviews     Review now
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            High-flow nasal cannula versus conventional oxygen therapy after endotracheal extubation: a randomized crossover physiologic study.

            Pitchayapa Rujiwit, Nuttapol Rittayamai, Jamsak Tscheikuna (2014)
            Compare the short-term benefit of high-flow nasal cannula (HFNC) with non-rebreathing mask in terms of change in dyspnea, physiologic variables, and patient comfort in subjects after endotracheal extubation. A randomized crossover study was conducted in a 10-bed respiratory care unit in a university hospital. Seventeen mechanically ventilated subjects were randomized after extubation to either Protocol A (applied HFNC for 30 min, followed by non-rebreathing mask for another 30 min) or Protocol B (applied non-rebreathing mask for 30 min, followed by HFNC for another 30 min). The level of dyspnea, breathing frequency, heart rate, blood pressure, oxygen saturation, and patient comfort were recorded. The results were expressed as mean ± SD, frequency, or percentage. Categorical variables were compared by chi-square test or Fisher exact test, and continuous variables were compared by dependent or paired t test. Statistical significance was defined as P < .05. Seventeen subjects were divided into 2 groups: 9 subjects in Protocol A and 8 subjects in Protocol B. The baseline characteristics and physiologic parameters before extubation were not significantly different in each protocol. At the end of study, HFNC indicated less dyspnea (P = .04) and lower breathing frequency (P = .009) and heart rate (P = .006) compared with non-rebreathing mask. Most of the subjects (88.2%) preferred HFNC to non-rebreathing mask. HFNC can improve dyspnea and physiologic parameters, including breathing frequency and heart rate, in extubated subjects compared with conventional oxygen therapy. This device may have a potential role for use after endotracheal extubation.
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              High-flow oxygen and bilevel positive airway pressure for persistent dyspnea in patients with advanced cancer: a phase II randomized trial.

              David Hui, Margarita Morgado (2013)
              Dyspnea is one of the most distressing symptoms for cancer patients. The role of high-flow oxygen (HFO) and bilevel positive airway pressure (BiPAP) in the palliation of dyspnea has not been well characterized.
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                Author and article information

                Journal
                Title: The Clinical Respiratory Journal
                Abbreviated Title: Clin Respir J
                Publisher: Wiley
                ISSN: 17526981
                Publication date Created: June 2018
                Publication date (Print): June 2018
                Publication date (Electronic): March 05 2018
                Volume: 12
                Issue: 6
                Pages: 2046-2056
                Affiliations
                [1 ]Department of Internal Medicine; Yonsei University Wonju College of Medicine; Wonju Gangwon South Korea
                [2 ]Institute of Lifestyle Medicine; Yonsei University Wonju College of Medicine; Wonju Gangwon South Korea
                Article
                DOI: 10.1111/crj.12772
                PubMed ID: 29392846
                SO-VID: 0b6e9c6d-dc14-4a0a-9cc1-4e81c5b6ca6a
                Copyright © © 2018
                License:

                http://doi.wiley.com/10.1002/tdm_license_1.1

                http://onlinelibrary.wiley.com/termsAndConditions#vor

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